Ionic Liquid-Phase Organic Synthesis (IoLiPOS) Methodology Applied to Cross Aldol Reaction

被引：2
作者：
Hakkou, H. [1 ]
Carrie, D. [1 ]
Paquin, L. [1 ]
Bazureau, J-P. [1 ]
机构：
[1] Univ Rennes 1, Lab Sci Chim Rennes, UMR CNRS 6226, Grp Ingn Chim & Mol Vivant ICMV, F-35042 Rennes, France
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 47卷 / 03期
关键词：
Ionic Liquid; Aldol; Cyclopentanone; Aldol Reaction; MeONa;
D O I：
10.1134/S1070428011030079
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Cross aldol reaction in task-specific ionic liquids was developed. Ionic liquid-phase bound aldehyde reacted with various ketones (acetone, cyclopentanone, and butan-2-one) with L-proline as catalyst to afford various ionic liquid-phase supported aldols in yields ranging from 81 to 99%. Detachment of the aldol in MeOH was realized by transesterification using 15% of MeONa. The structure of intermediates in each step was verified by spectroscopic analysis.
引用
收藏
页码：371 / 373
页数：3
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