RNA as a drug target: The case of aminoglycosides

被引：176
作者：
Vicens, Q [1 ]
Westhof, E [1 ]
机构：
[1] Univ Strasbourg 1, CNRS, Inst Biol Mol & Cellulaire, UPR 9002, F-67084 Strasbourg, France
来源：
CHEMBIOCHEM | 2003年 / 4卷 / 10期
关键词：
aminoglycosides; antibiotics; ribosomes; RNA; RNA recognition; RNA structure;
D O I：
10.1002/cbic.200300684
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：1018 / 1023
页数：6
相关论文
共 88 条
[1]   Altered expression of oligopeptide-binding protein (OppA) and aminoglycoside resistance in laboratory and clinical Escherichia coli strains [J].
Acosta, MBR ;
Ferreira, RCC ;
Padilla, G ;
Ferreira, LCS ;
Costa, SOP .
JOURNAL OF MEDICAL MICROBIOLOGY, 2000, 49 (05) :409-413
[2]   Gentamicin nephrotoxicity in humans and animals: Some recent research [J].
Ali, BH .
GENERAL PHARMACOLOGY, 1995, 26 (07) :1477-1487
[3]  
Auerbach Tamar, 2002, Current Drug Targets - Infectious Disorders, V2, P169, DOI 10.2174/1568005023342506
[4]   Hydration of RNA base pairs [J].
Auffinger, P ;
Westhof, E .
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1998, 16 (03) :693-707
[5]   Melting of the solvent structure around a RNA duplex: a molecular dynamics simulation study [J].
Auffinger, P ;
Westhof, E .
BIOPHYSICAL CHEMISTRY, 2002, 95 (03) :203-210
[6]  
Barbachyn M.R., 2003, Angew. Chem, V115, P2056
[7]   Oxazolidinone structure-activity relationships leading to linezolid [J].
Barbachyn, MR ;
Ford, CW .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (18) :2010-2023
[8]   G-418, AN ELONGATION INHIBITOR OF 80-S RIBOSOMES [J].
BARNUN, S ;
SHNEYOUR, Y ;
BECKMANN, JS .
BIOCHIMICA ET BIOPHYSICA ACTA, 1983, 741 (01) :123-127
[9]   Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression [J].
Bashan, A ;
Agmon, I ;
Zarivach, R ;
Schluenzen, F ;
Harms, J ;
Berisio, R ;
Bartels, H ;
Franceschi, F ;
Auerbach, T ;
Hansen, HAS ;
Kossoy, E ;
Kessler, M ;
Yonath, A .
MOLECULAR CELL, 2003, 11 (01) :91-102
[10]  
Batey RT, 1999, ANGEW CHEM INT EDIT, V38, P2327
123456789