Previous research is conflicting concerning the minimum time duration needed to elicit a growth hormone (GH) response to aerobic exercise; thus, the purpose of this project was to examine the effects of mode and duration on exercise-induced GH responses in young women taking oral contraceptives. Nine healthy young females on oral contraceptives exercised at 75% of their mode-specific peak aerobic power (V.O(2)peak) on the treadmill and cycle ergometer for 10, 15 and 20 min, with serial blood samples taken at rest and every 10 min throughout the entire 5.5 h of the study. Each exercise bout was followed by 70 min of rest. A significant (P<0.02) GH response was observed at the end of exercise regardless of the duration or mode of exercise. The peak GH concentrations were 12.2 (1.8), 10.2 (1.6), and 7.6 (1.5) ng.ml(-1) for the 10-, 15-, and 20-min exercise bouts on the treadmill, respectively. For the cycle ergometer, peak GH concentrations were 9.3 (2.0), 6.3 (1.0), and 9.8 (1.7) ng.ml(-1), respectively. The total integrated area under the curve was not significantly different between the cycle and treadmill exercise for each exercise duration. Moderate-intensity aerobic exercise is sufficient to produce a GH response in as little as 10 min during both treadmill and cycling exercise in young women taking oral contraceptives. Overall, the mode of exercise does not impact the exercise-induced GH response.