Antibiotic susceptibility of bacterial strains isolated from lower urinary tract infection in 2018 in Zabol: A cross-sectional study

This study aim was the determining antibiotic sensitivity pattern of most probable pathogens is a major determinant of successful empiric therapy. A cross-sectional study conducted on 465 patients with UTI. In this study the antibiotic susceptibility pattern of bacterial strains isolated from lower urinary tract infections was investigated. Bacterial identification and antibiotic sensitivity testing using disk diffusion method were performed on positive cultures. One hundred and five positive cultures were obtained; 12.4% males and 87.6% females. Escherichia coli and Staphylococcus spp. were the most common isolated uropathogens. Among E. coil and S. epidermidis isolates, the highest susceptibility was observed to ciprofloxacin, and the lowest to ampicillin. Four isolates (3.8%) were susceptible to all tested antimicrobials, and 87 (82.9%) exhibited resistance to at least two different classes of antibiotics. E. coil and S. epidermidis were major causes of community-acquired UTI in the test society and were resistant to several antibiotics. Based on these results, ciprofloxacin and Nitrofurantoin were recommended as preferred agents for empiric therapy of UTI.