The methodology of an integrated simulation system application for decision-making support in enterprises is described in this article. The use of visual interactive modelling and animation can help users better understand simulation results, especially those who are not experts. Decision-makers are motivated by the animation while seeking better solutions for production problems. The method was tested in a medium-sized company in order to improved operational planning and re-engineering. The real process was recorded on video, digitized, and implemented on a PC. Animation of the simulated process, synchronized with video of the real process, was projected in a room to achieve model validation and participant confidence. Operational production plans were simulated using current demands as the basis. Application of discrete event simulation in reengineering is also presented. The article shows how to develop a model, prepare scenarios and evaluate alternatives. Two criteria were evaluated for the alternative: the expected value and the value of multiple criteria evaluation, which was examined with the AHP method. Model validation and its use for alternative selection is also discussed.