Diffuse optical tomography using multidirectional sources and detectors

被引:11
|
作者
Shimokawa, Takeaki [1 ]
Ishii, Toshihiro [2 ]
Takahashi, Yoichiro [2 ]
Sugawara, Satoru [2 ]
Sato, Masa-aki [1 ]
Yamashita, Okito [1 ,3 ]
机构
[1] ATR Neural Informat Anal Labs, Kyoto 6190288, Japan
[2] RICOH Co Ltd, Ricoh Inst Future Technol, Natori, Miyagi 9811241, Japan
[3] CiNet, Brain Funct Imaging Technol Grp, Osaka 5650871, Japan
来源
BIOMEDICAL OPTICS EXPRESS | 2016年 / 7卷 / 07期
关键词
SPATIAL-RESOLUTION; SPECTROSCOPY; VALIDATION; ACTIVATION;
D O I
10.1364/BOE.7.002623
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Diffuse optical tomography (DOT) is an advanced imaging method used to visualize the internal state of biological tissues as 3D images. However, current continuous-wave DOT requires high-density probe arrays for measurement (less than 15-mm interval) to gather enough information for 3D image reconstruction, which makes the experiment time-consuming. In this paper, we propose a novel DOT measurement system using multi-directional light sources and multi-directional photodetectors instead of high-density probe arrays. We evaluated this system's multi-directional DOT through computer simulation and a phantom experiment. From the results, we achieved DOT with less than 5-mm localization error up to a 15-mm depth with low-density probe arrays (30-mm interval), indicating that the multi-directional measurement approach allows DOT without requiring high-density measurement. (C) 2016 Optical Society of America
引用
收藏
页码:2623 / 2640
页数:18
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