Kinetic analysis of the effects of products removal on the hydrolysis of penicillin G by immobilised penicillin acylase

被引:15
作者
Duan, G
Chen, JY
机构
[1] Institute of Chemical Metallurgy, Academia Sinica, Beijing
关键词
D O I
10.1016/0032-9592(95)00017-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The effects of products removal on the hydrolysis of penicillin G by immobilised penicillin acylase were studied by kinetic simulation. Analysis of the substrate and products inhibition data from the literature for this kinetically controlled reaction shows that the removal of phenylacetic acid (PAA) as produced in this reaction has little effect on the reaction rate.
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页码:27 / 30
页数:4
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