Magnetic hyperthermia: Potentials and limitations

被引:89
作者
Peiravi, Mozhdeh [1 ]
Eslami, Hossein [1 ]
Ansari, Mojtaba [1 ]
Zare-Zardini, Hadi [1 ,2 ,3 ]
机构
[1] Meybod Univ, Dept Biomed Engn, Meybod, Iran
[2] Shahid Sadoughi Univ Med Sci, Hematol & Oncol Res Ctr, Yazd, Iran
[3] Shahid Sadoughi Univ Med Sci, Yazd Reprod Sci Inst, Med Nanotechnol & Tissue Engn Res Ctr, Yazd, Iran
关键词
Magnetic; Hyperthermia; Cancer therapy; IRON-OXIDE NANOPARTICLES; RANDOMIZED PHASE-III; RADIATION-THERAPY; COFE2O4; NANOPARTICLES; FLUID HYPERTHERMIA; CELL-DEATH; CANCER; TRIAL; THERMORADIOTHERAPY; RADIOTHERAPY;
D O I
10.1016/j.jics.2021.100269
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Despite the fact that the magnetic hyperthermia (MH) has been known for more than 75 years, it is still debated in its clinical applications. The generation of a higher temperature at a tumor is called hyperthermia. There is a different of temperature ranges going from 39 to 40 degrees C up to such high temperatures as 80-90 degrees C. However, due to its high potential, MH is used along with nanoparticles as heat intermediaries in the treatment of cancer. Many Magnetic Nanoparticles (MNPs) with several properties and morphological metallic structures have been useful to magnetics hyperthermia therapy. These MNPs are categorized into two groups; magnetic alloy nanoparticles (MANPs) and magnetic metal oxide nanoparticles (MMONPs). The principal challenges of this method are the control of local tumoral temperature and the increase in nanoparticles heating power. The hyperthermia agents derived from magnetic nanoparticles along with magnetic field. In the recent study, hyperthermia thought, dis -similar types of magnetic nanoparticles for hyperthermia, efficacy for cancer therapy, advances, challenges, and future chances have been examined.
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页数:11
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