An Overview of the Latest Graphene-Based Sensors for Glucose Detection: the Effects of Graphene Defects

被引:81
作者
Carbone, Marilena [1 ]
Gorton, Lo [2 ]
Antiochia, Riccarda [3 ]
机构
[1] Univ Roma Tor Vergata, Dept Chem Sci & Technol, I-00133 Rome, Italy
[2] Lund Univ, Dept Analyt Chem Biochem & Struct Biol, SE-22100 Lund, Sweden
[3] Univ Roma La Sapienza, Dept Chem & Drug Technol, I-00185 Rome, Italy
基金
瑞典研究理事会;
关键词
Graphene-based sensors; Glucose detection; Defects; Heterogeneous electron/proton transfer constant; GLASSY-CARBON ELECTRODE; DIRECT ELECTROCHEMISTRY; CELLOBIOSE DEHYDROGENASE; FUNCTIONALIZED GRAPHENE; BIOSENSING PLATFORM; OXIDIZED GRAPHENE; GRAPHITE OXIDE; DOPED GRAPHENE; NANOTUBES; NANOCOMPOSITE;
D O I
10.1002/elan.201400409
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In this review, we analyze several types of graphene-based sensors for glucose detection with respect to their preparation, properties and efficiency in electro-chemical processes. Graphene may display different types of defects, which play a role in the electron transfer processes. Oxygenated groups on the edges of graphene planes reduce the graphene in-plane conductivity, but may enhance the heterogeneous electron/proton transfer constant. Other positive effects of defects are related to the shortening of the distance between active centers and electrodes upon enzyme or protein immobilization. However, though by different mechanisms, all types of graphene enhance the electrochemical response at the electrode.
引用
收藏
页码:16 / 31
页数:16
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