Free radical scavenging, anti-glycation and tyrosinase inhibition properties of a polysaccharide fraction isolated from the rind from Punica granatum

被引：111

作者：

Rout, S. ^{[1
]}

Banerjee, R. ^{[1
]}

机构：

[1] Indian Inst Technol, Agr & Food Engn Dept, Microbial Biotechnol & Downstream Proc Lab, Kharagpur 721302, W Bengal, India

来源：

BIORESOURCE TECHNOLOGY | 2007年 / 98卷 / 16期

关键词：

pomegranate; DPPH; ABTS(+); reducing power; fructosamine; tyrosinase;

D O I：

10.1016/j.biortech.2006.10.011

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

The present investigation deals with the isolation of a polysaccharide fraction from Pomegranate (PFP), which was found to inhibit 1,1-diphenyl-1-2-picrylhydrazyl (DPPH) and 2,2'-Azinobis[3-ethylbenzothiazoline-6-sulfonate] ABTS-(+) radical activities by 69% and 88%, respectively with 4 mu g/ml concentration. The activity of PFP for free radical scavenging was also evaluated by electron spin resonance (ESR) Spectrophotorneter and DPPH dot blot test. Anti-glycation ability of PFP was tested using BSA, which inhibited the formation of advanced glycation end-products (AGEs) by 28% and also inhibited the formation of fructosamine in the BSA/Glucose system. The inhibition of mushroom tyrosinase by 43% at 10 mu g/ml concentration of PFP strongly suggested its efficacy as a possible skin whitener. (C) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3159 / 3163

页数：5

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