Pharmacokinetic Interactions between Cardiovascular Medicines and Plant Products

被引：10
|
作者：
Costache, Irina-Iuliana [1 ,2 ]
Miron, Anca [3 ]
Hancianu, Monica [3 ]
Aursulesei, Viviana [1 ,2 ]
Costache, Alexandru Dan [1 ]
Aprotosoaie, Ana Clara [3 ]
机构：
[1] Grigore T Popa Univ Med & Pharm Iasi, Fac Med, Iasi 700115, Romania
[2] Sf Spiridon Univ Hosp, Iasi 700111, Romania
[3] Grigore T Popa Univ Med & Pharm Iasi, Fac Pharm, Iasi 700115, Romania
来源：
CARDIOVASCULAR THERAPEUTICS | 2019年 / 2019卷
关键词：
ST-JOHNS-WORT; INCREASES SERUM CONCENTRATIONS; JUICE-FELODIPINE INTERACTION; HERB-DRUG INTERACTIONS; GRAPEFRUIT JUICE; GINKGO-BILOBA; GREEN TEA; PLASMA-CONCENTRATIONS; DIETARY-SUPPLEMENTS; P-GLYCOPROTEIN;
D O I：
10.1155/2019/9402781
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The growing use of plant products among patients with cardiovascular pharmacotherapy raises the concerns about their potential interactions with conventional cardiovascular medicines. Plant products can influence pharmacokinetics or/and pharmacological activity of coadministered drugs and some of these interactions may lead to unexpected clinical outcomes. Numerous studies and case reports showed various pharmacokinetic interactions that are characterized by a high degree of unpredictability. This review highlights the pharmacokinetic clinically relevant interactions between major conventional cardiovascular medicines and plant products with an emphasis on their putative mechanisms, drawbacks of herbal products use, and the perspectives for further well-designed studies.
引用
收藏
页数：19
相关论文
共 50 条
  • [31] CARDIOVASCULAR AND PHARMACOKINETIC DRUG-INTERACTIONS BETWEEN ACUTE TIRILAZAD MESYLATE AND CHRONIC NIMODIPINE IN CONSCIOUS DOGS
    HUMPHREY, SJ
    WEBER, DJ
    SMITH, MP
    BROWN, WP
    STEENWYK, RC
    LUND, JE
    DRUG DEVELOPMENT RESEARCH, 1993, 28 (02) : 141 - 152
  • [32] Medicines for older people: assessment and transparency at the European Medicines Agency regarding cardiovascular and antithrombotic medicinal products
    Francesca Cerreta
    Andreia Padrão
    Izabela Skibicka-Stepien
    Anna Strampelli
    Maria Silvia de Orbe Izquierdo
    European Geriatric Medicine, 2018, 9 : 415 - 418
  • [33] An audit on the management of drug interactions between antiretroviral medicines and anticoagulants and/or antiplatelet medicines
    Payghamy-Ashnai, N.
    Naous, N.
    Weston, R.
    Garvey, L.
    Mackie, N.
    HIV MEDICINE, 2019, 20 : 16 - 17
  • [34] Pharmacokinetic Drug Interactions with Tobacco, Cannabinoids and Smoking Cessation Products
    Anderson, Gail D.
    Chan, Lingtak-Neander
    CLINICAL PHARMACOKINETICS, 2016, 55 (11) : 1353 - 1368
  • [35] Pharmacokinetic Drug Interactions with Tobacco, Cannabinoids and Smoking Cessation Products
    Gail D. Anderson
    Lingtak-Neander Chan
    Clinical Pharmacokinetics, 2016, 55 : 1353 - 1368
  • [36] PHARMACOKINETIC AND PHARMACODYNAMIC INTERACTIONS BETWEEN CAFFEINE AND DIAZEPAM
    GHONEIM, MM
    HINRICHS, JV
    CHIANG, CK
    LOKE, WH
    JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 1986, 6 (02) : 75 - 80
  • [37] Pharmacokinetic Interactions Between Alcohol and Other Drugs
    Alan G. Fraser
    Clinical Pharmacokinetics, 1997, 33 : 79 - 90
  • [38] PHARMACOKINETIC AND PHARMACODYNAMIC INTERACTIONS BETWEEN FENTANYL AND BUPRENORPHINE
    GERLACH, H
    GIPS, H
    RICHTER, M
    BORNER, U
    GERLACH, I
    ANAESTHESIST, 1984, 33 (09): : 458 - 458
  • [39] Pharmacokinetic and pharmacokdynamic interactions between zolpidem and caffeine
    Farkas, D
    Cysneiros, RM
    Harmatz, JS
    von Moltke, LL
    Greenblatt, DJ
    JOURNAL OF CLINICAL PHARMACOLOGY, 2005, 45 (09): : 1081 - 1081
  • [40] PHARMACOKINETIC INTERACTIONS BETWEEN CYCLOSPORINE AND OTHER DRUGS
    YEE, GC
    TRANSPLANTATION PROCEEDINGS, 1990, 22 (03) : 1203 - 1207
12345