Assessment of medication self-administration using artificial intelligence

被引:44
作者
Zhao, Mingmin [1 ]
Hoti, Kreshnik [1 ,2 ]
Wang, Hao [1 ]
Raghu, Aniruddh [1 ]
Katabi, Dina [1 ]
机构
[1] MIT, Comp Sci & Artificial Intelligence Lab, 77 Massachusetts Ave, Cambridge, MA 02139 USA
[2] Univ Prishtina, Fac Med, Div Pharm, Prishtina, Kosovo
关键词
INHALER TECHNIQUE; ADHERENCE; BARRIERS; ASTHMA; ERRORS;
D O I
10.1038/s41591-021-01273-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Artificial intelligence coupled with wireless home sensors can monitor the use of insulin pens and inhalers by patients and alert of errors in self-medication in an unobtrusive manner. Errors in medication self-administration (MSA) lead to poor treatment adherence, increased hospitalizations and higher healthcare costs. These errors are particularly common when medication delivery involves devices such as inhalers or insulin pens. We present a contactless and unobtrusive artificial intelligence (AI) framework that can detect and monitor MSA errors by analyzing the wireless signals in the patient's home, without the need for physical contact. The system was developed by observing self-administration conducted by volunteers and evaluated by comparing its prediction with human annotations. Findings from this study demonstrate that our approach can automatically detect when patients use their inhalers (area under the curve (AUC) = 0.992) or insulin pens (AUC = 0.967), and assess whether patients follow the appropriate steps for using these devices (AUC = 0.952). The work shows the potential of leveraging AI-based solutions to improve medication safety with minimal overhead for patients and health professionals.
引用
收藏
页码:727 / 735
页数:13
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