A 60-year-old woman with agitation and psychosis following ingestion of dextromethorphan and opioid analgesics

被引：3

作者：

Jamison, S. C. ^{[1
]}

Vasudeva, S. ^{[1
]}

机构：

[1] Carilion Clin, Roanoke, VA USA

来源：

JOURNAL OF PSYCHOPHARMACOLOGY | 2009年 / 23卷 / 08期

关键词：

delirium; dextromethorphan; pharmacodynamics; propoxyphene; serotonin; PSEUDOEPHEDRINE; OLANZAPINE; ABUSE;

D O I：

10.1177/0269881108092125

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A patient presented with agitation, paranoia, and psychosis following ingestion of dextromethorphan, propoxyphene, and hydrocodone, a previously unreported combination. Symptoms resolved with antipsychotics and cessation of offending drugs. The pharmacodynamics of dextromethorphan and the opioids, including drug interactions are discussed, and several potential mechanisms for the production of the patient's symptoms are proposed.

引用

页码：989 / 991

页数：3