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- [21] Integration of risk factor polygenic risk score with disease polygenic risk score for disease predictionCommunications Biology, 7Hyein Jung论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee University,Department of Biomedical Science, Graduate SchoolHae-Un Jung论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee University,Department of Biomedical Science, Graduate SchoolEun Ju Baek论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee University,Department of Biomedical Science, Graduate SchoolShin Young Kwon论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee University,Department of Biomedical Science, Graduate SchoolJi-One Kang论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee University,Department of Biomedical Science, Graduate SchoolJi Eun Lim论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee University,Department of Biomedical Science, Graduate SchoolBermseok Oh论文数: 0 引用数: 0 h-index: 0机构: Kyung Hee University,Department of Biomedical Science, Graduate School
- [22] Evaluation of a Multiethnic Polygenic Risk Score Model for Prostate CancerJNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2022, 114 (05): : 771 - 774Plym, Anna论文数: 0 引用数: 0 h-index: 0机构: Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USA Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USAPenney, Kathryn L.论文数: 0 引用数: 0 h-index: 0机构: Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA Brigham & Womens Hosp, Dept Med, Channing Div Network Med, Boston, MA USA Harvard Med Sch, Boston, MA 02115 USA Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USAKalia, Sarah论文数: 0 引用数: 0 h-index: 0机构: Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USAKraft, Peter论文数: 0 引用数: 0 h-index: 0机构: Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA Harvard TH Chan Sch Publ Hlth, Program Genet Epidemiol & Stat Genet, Boston, MA USA Harvard TH Chan Sch Publ Hlth, Dept Biostat, Boston, MA USA Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USAConti, David, V论文数: 0 引用数: 0 h-index: 0机构: Univ Southern Calif, Ctr Genet Epidemiol, Keck Sch Med, Dept Prevent Med,Norris Comprehens Canc Ctr, Los Angeles, CA USA Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USAHaiman, Christopher论文数: 0 引用数: 0 h-index: 0机构: Univ Southern Calif, Ctr Genet Epidemiol, Keck Sch Med, Dept Prevent Med,Norris Comprehens Canc Ctr, Los Angeles, CA USA Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USAMucci, Lorelei A.论文数: 0 引用数: 0 h-index: 0机构: Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USAKibel, Adam S.论文数: 0 引用数: 0 h-index: 0机构: Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USA Harvard Med Sch, Brigham & Womens Hosp, Dept Surg, Urol Div, 45 Francis St, Boston, MA 02115 USA
- [23] Evaluation of modifiable factors and polygenic risk score in thyroid cancerENDOCRINE-RELATED CANCER, 2021, 28 (07) : 481 - 494Hoang, Tung论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South Korea Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South KoreaQuy Nguyen Ngoc论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Dept Canc Control & Populat Hlth, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South Korea Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South KoreaLee, Jeonghee论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South Korea Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South KoreaLee, Eun Kyung论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Ctr Thyroid Canc, Goyang, Gyeonggi Do, South Korea Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South KoreaHwangbo, Yul论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Ctr Thyroid Canc, Goyang, Gyeonggi Do, South Korea Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South KoreaKim, Jeongseon论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South Korea Natl Canc Ctr, Dept Canc Biomed Sci, Grad Sch Canc Sci & Policy, Goyang, Gyeonggi Do, South Korea
- [24] Polygenic Risk Score for Risk AssessmentJOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S301 - S302论文数: 引用数: h-index:机构:Brhane, Y.论文数: 0 引用数: 0 h-index: 0机构: Sinai Hlth Syst, Lunenfeld Tanenbaum Res Inst, Prosserman Ctr Populat Hlth Res, Toronto, ON, Canada Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaChatterjie, N.论文数: 0 引用数: 0 h-index: 0机构: Johns Hopkins Univ, Baltimore, MD USA Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaChristiani, D.论文数: 0 引用数: 0 h-index: 0机构: Harvard Sch Publ Hlth, Environm Hlth, Epidemiol, Boston, MA USA Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaCaporaso, N.论文数: 0 引用数: 0 h-index: 0机构: NCI, Bethesda, MD 20892 USA Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaLandi, M.论文数: 0 引用数: 0 h-index: 0机构: NCI, Bethesda, MD 20892 USA Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaLe Marchand, L.论文数: 0 引用数: 0 h-index: 0机构: Univ Hawaii, Ctr Canc, Honolulu, HI 96822 USA Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaLiu, G.论文数: 0 引用数: 0 h-index: 0机构: Princess Margaret Canc Ctr, Toronto, ON, Canada Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaLam, S.论文数: 0 引用数: 0 h-index: 0机构: British Columbia Canc Agcy, Integrat Oncol, Vancouver, BC, Canada Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaField, J.论文数: 0 引用数: 0 h-index: 0机构: Univ Liverpool, Canc Res Ctr, Liverpool, Merseyside, England Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaBrennan, P.论文数: 0 引用数: 0 h-index: 0机构: Interat Agcy Res Canc, Lyon, France Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, CanadaAmos, C.论文数: 0 引用数: 0 h-index: 0机构: Baylor Coll Med, Houston, TX 77030 USA Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
- [25] Performance of a polygenic risk score combined with clinical assessment for breast cancer riskCANCER RESEARCH, 2020, 80 (04)Black, Mary Helen论文数: 0 引用数: 0 h-index: 0机构: Ambry Genet, Aliso Viejo, CA USA Ambry Genet, Aliso Viejo, CA USALi, Shuwei论文数: 0 引用数: 0 h-index: 0机构: Ambry Genet, Aliso Viejo, CA USA Ambry Genet, Aliso Viejo, CA USALaDuca, Holly论文数: 0 引用数: 0 h-index: 0机构: Ambry Genet, Aliso Viejo, CA USA Ambry Genet, Aliso Viejo, CA USAArmasu, Sebastian论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USAPolley, Eric C.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USAFitz-Gibbon, Patrick论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USAScott, Chris G.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USAWinham, Stacey J.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USAOlson, Janet E.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USARuddy, Kathryn J.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USAVachon, Celine M.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USACouch, Fergus J.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Rochester, MN USA Ambry Genet, Aliso Viejo, CA USA
- [26] Evaluating the prognostic performance of a polygenic risk score for breast cancer risk stratificationBMC Cancer, 21Maria Olsen论文数: 0 引用数: 0 h-index: 0机构: Amsterdam University Medical Centers,Department of Clinical Epidemiology, Biostatistics and BioinformaticsKrista Fischer论文数: 0 引用数: 0 h-index: 0机构: Amsterdam University Medical Centers,Department of Clinical Epidemiology, Biostatistics and BioinformaticsPatrick M. Bossuyt论文数: 0 引用数: 0 h-index: 0机构: Amsterdam University Medical Centers,Department of Clinical Epidemiology, Biostatistics and BioinformaticsEls Goetghebeur论文数: 0 引用数: 0 h-index: 0机构: Amsterdam University Medical Centers,Department of Clinical Epidemiology, Biostatistics and Bioinformatics
- [27] Evaluating the prognostic performance of a polygenic risk score for breast cancer risk stratificationBMC CANCER, 2021, 21 (01)Olsen, Maria论文数: 0 引用数: 0 h-index: 0机构: Amsterdam Univ Med Ctr, Amsterdam Publ Hlth Res Inst, Dept Clin Epidemiol Biostat & Bioinformat, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands Amsterdam Univ Med Ctr, Amsterdam Publ Hlth Res Inst, Dept Clin Epidemiol Biostat & Bioinformat, Meibergdreef 9, NL-1105 AZ Amsterdam, NetherlandsFischer, Krista论文数: 0 引用数: 0 h-index: 0机构: Univ Tartu, Inst Math & Stat, Narva Mnt 18, EE-51009 Tartu, Estonia Univ Tartu, Estonian Genome Ctr, Inst Genom, Tartu, Estonia Amsterdam Univ Med Ctr, Amsterdam Publ Hlth Res Inst, Dept Clin Epidemiol Biostat & Bioinformat, Meibergdreef 9, NL-1105 AZ Amsterdam, NetherlandsBossuyt, Patrick M.论文数: 0 引用数: 0 h-index: 0机构: Amsterdam Univ Med Ctr, Amsterdam Publ Hlth Res Inst, Dept Clin Epidemiol Biostat & Bioinformat, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands Amsterdam Univ Med Ctr, Amsterdam Publ Hlth Res Inst, Dept Clin Epidemiol Biostat & Bioinformat, Meibergdreef 9, NL-1105 AZ Amsterdam, NetherlandsGoetghebeur, Els论文数: 0 引用数: 0 h-index: 0机构: Univ Ghent, Inst Continuing Educ, Dept Appl Math Comp Sci & Stat, Ctr Stat, Campus Sterre,S9,Krijgslaan 281, B-9000 Ghent, Belgium Amsterdam Univ Med Ctr, Amsterdam Publ Hlth Res Inst, Dept Clin Epidemiol Biostat & Bioinformat, Meibergdreef 9, NL-1105 AZ Amsterdam, Netherlands
- [28] Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score CatalogBMJ MEDICINE, 2023, 2 (01):Hingorani, Aroon D.论文数: 0 引用数: 0 h-index: 0机构: UCL, Inst Cardiovasc Sci, London WC1E 6BT, England UCL, British Heart Fdn Res Accelerator, London, England Univ Coll London Hosp, Natl Inst Hlth Res, Biomed Res Ctr, London, England Hlth Data Res UK, London, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, EnglandGratton, Jasmine论文数: 0 引用数: 0 h-index: 0机构: UCL, Inst Cardiovasc Sci, London WC1E 6BT, England UCL, British Heart Fdn Res Accelerator, London, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, EnglandFinan, Chris论文数: 0 引用数: 0 h-index: 0机构: UCL, Inst Cardiovasc Sci, London WC1E 6BT, England UCL, British Heart Fdn Res Accelerator, London, England Univ Coll London Hosp, Natl Inst Hlth Res, Biomed Res Ctr, London, England Hlth Data Res UK, London, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, EnglandSchmidt, A. Floriaan论文数: 0 引用数: 0 h-index: 0机构: UCL, Inst Cardiovasc Sci, London WC1E 6BT, England Univ Coll London Hosp, Natl Inst Hlth Res, Biomed Res Ctr, London, England Hlth Data Res UK, London, England Univ Med Ctr Utrecht, Utrecht, Netherlands UCL, Inst Cardiovasc Sci, London WC1E 6BT, EnglandPatel, Riyaz论文数: 0 引用数: 0 h-index: 0机构: UCL, Inst Cardiovasc Sci, London WC1E 6BT, England UCL, British Heart Fdn Res Accelerator, London, England Univ Coll London Hosp, Natl Inst Hlth Res, Biomed Res Ctr, London, England Hlth Data Res UK, London, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, EnglandSofat, Reecha论文数: 0 引用数: 0 h-index: 0机构: Hlth Data Res UK, London, England Univ Liverpool, Dept Pharmacol & Therapeut, Liverpool, Merseyside, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, EnglandKuan, Valerie论文数: 0 引用数: 0 h-index: 0机构: UCL, Inst Cardiovasc Sci, London WC1E 6BT, England UCL, British Heart Fdn Res Accelerator, London, England Univ Coll London Hosp, Natl Inst Hlth Res, Biomed Res Ctr, London, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, England论文数: 引用数: h-index:机构:Hemingway, Harry论文数: 0 引用数: 0 h-index: 0机构: UCL, British Heart Fdn Res Accelerator, London, England Univ Coll London Hosp, Natl Inst Hlth Res, Biomed Res Ctr, London, England Hlth Data Res UK, London, England UCL, Inst Hlth Informat, London, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, EnglandMorris, Joan K.论文数: 0 引用数: 0 h-index: 0机构: St Georges Univ London, Populat Hlth Res Inst, London, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, EnglandWald, Nicholas J.论文数: 0 引用数: 0 h-index: 0机构: UCL, Inst Hlth Informat, London, England St Georges Univ London, Populat Hlth Res Inst, London, England UCL, Inst Cardiovasc Sci, London WC1E 6BT, England
- [29] A Novel Method to Estimate Polygenic Risk Scores in Admixed PopulationsGENETIC EPIDEMIOLOGY, 2021, 45 (07) : 798 - 799Wang, Xuexia论文数: 0 引用数: 0 h-index: 0机构: Univ North Texas, Dept Math, Denton, TX 76203 USA Univ North Texas, Dept Math, Denton, TX 76203 USAXie, Sicong论文数: 0 引用数: 0 h-index: 0机构: Beijing Natl Day Sch, Beijing, Peoples R China Univ North Texas, Dept Math, Denton, TX 76203 USADoyle, Callum论文数: 0 引用数: 0 h-index: 0机构: Univ North Texas, Dept Math, Denton, TX 76203 USA Univ North Texas, Dept Math, Denton, TX 76203 USA
- [30] Obsessive-Compulsive Symptoms, Polygenic Risk Score, and Thalamic Development in Children From the Brazilian High-Risk Cohort for Mental Conditions (BHRCS)FRONTIERS IN PSYCHIATRY, 2021, 12Ravagnani Salto, Ana Beatriz论文数: 0 引用数: 0 h-index: 0机构: Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilSantoro, Marcos L.论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Sao Paulo, Dept Morfol & Genet, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilHoexter, Marcelo Q.论文数: 0 引用数: 0 h-index: 0机构: Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilJackowski, Andrea Parolin论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Sao Paulo, Dept Psiquiatria, Lab Integrat Neurosci, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilPan, Pedro M.论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Sao Paulo, Dept Psiquiatria, Lab Integrat Neurosci, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilRosario, Maria Conceicao论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Sao Paulo, Dept Psiquiatria, Lab Integrat Neurosci, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilBelangero, Sintia, I论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Sao Paulo, Dept Morfol & Genet, Sao Paulo, Brazil Univ Fed Sao Paulo, Dept Psiquiatria, Lab Integrat Neurosci, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilAlvarenga, Pedro Gomes论文数: 0 引用数: 0 h-index: 0机构: Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilDoretto, Victoria Fogaca论文数: 0 引用数: 0 h-index: 0机构: Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilTiago Fumo, Afonso Mazine论文数: 0 引用数: 0 h-index: 0机构: Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilBatistuzzo, Marcelo C.论文数: 0 引用数: 0 h-index: 0机构: Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil Pontifical Catholic Univ, Dept Methods & Tech Psychol, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilFerreira de Barros, Pedro Macul论文数: 0 引用数: 0 h-index: 0机构: Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilTimpano, Kiara R.论文数: 0 引用数: 0 h-index: 0机构: Univ Miami, Dept Psychol, POB 248185, Coral Gables, FL 33124 USA Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilOta, Vanessa K.论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Sao Paulo, Dept Morfol & Genet, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilRohde, Luis Augusto论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Attent Deficit Hyperact Disorder & Dev Psychiat P, Porto Alegre, RS, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilMiguel, Euripedes Constantino论文数: 0 引用数: 0 h-index: 0机构: Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilLeckman, James F.论文数: 0 引用数: 0 h-index: 0机构: Yale Univ, Yale Child Study Ctr, Yale Sch Med, New Haven, CT USA Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, BrazilZugman, Andre论文数: 0 引用数: 0 h-index: 0机构: Univ Fed Sao Paulo, Dept Psiquiatria, Lab Integrat Neurosci, Sao Paulo, Brazil Univ Sao Paulo, Fac Med, Dept & Inst Psychiat, Sao Paulo, Brazil