Circulating Non-Coding RNAs in Head and Neck Cancer: Roles in Diagnosis, Prognosis, and Therapy Monitoring

被引：20

作者：

Diez-Fraile, Araceli ^{[1
]}

Ceulaer, Joke De ^{[1
]}

Derpoorter, Charlotte ^{[2
,3
,4
]}

Spaas, Christophe ^{[1
]}

Backer, Tom De ^{[1
]}

Lamoral, Philippe ^{[1
]}

Abeloos, Johan ^{[1
]}

Lammens, Tim ^{[2
,3
,4
]}

机构：

[1] AZ Sint Jan Brugge Oostende AV, Dept Surg, Div Oral & Maxillofacial Surg, B-8000 Brugge, Belgium

[2] Ghent Univ Hosp, Dept Pediat Hematol Oncol & Stem Cell Transplanta, B-9000 Ghent, Belgium

[3] Univ Ghent, Dept Internal Med & Pediat, B-9000 Ghent, Belgium

[4] Canc Res Inst Ghent CRIG, B-9000 Ghent, Belgium

来源：

CELLS | 2021年 / 10卷 / 01期

关键词：

head and neck cancer; circulating non-coding RNA; liquid biopsy; biomarkers;

D O I：

10.3390/cells10010048

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Head and neck cancer (HNC), the seventh most common form of cancer worldwide, is a group of epithelial malignancies affecting sites in the upper aerodigestive tract. The 5-year overall survival for patients with HNC has stayed around 40-50% for decades, with mortality being attributable mainly to late diagnosis and recurrence. Recently, non-coding RNAs, including tRNA halves, YRNA fragments, microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), have been identified in the blood and saliva of patients diagnosed with HNC. These observations have recently fueled the study of their potential use in early detection, diagnosis, and risk assessment. The present review focuses on recent insights and the potential impact that circulating non-coding RNA evaluation may have on clinical decision-making in the management of HNC.

引用

页码：1 / 13

页数：13

共 86 条

[1] Mutation in ADAT3, encoding adenosine deaminase acting on transfer RNA, causes intellectual disability and strabismus [J].

Alazami, Anas M. ;

Hijazi, Hadia ;

Al-Dosari, Mohammed S. ;

Shaheen, Ranad ;

Hashem, Amal ;

Aldahmesh, Mohammed A. ;

Mohamed, Jawahir Y. ;

Kentab, Amal ;

Salih, Mustafa A. ;

Awaji, Ali ;

Masoodi, Tariq A. ;

Alkuraya, Fowzan S. .

JOURNAL OF MEDICAL GENETICS, 2013, 50 (07) :425-430

[2] Noncoding RNA in development [J].

Amaral, Paulo P. ;

Mattick, John S. .

MAMMALIAN GENOME, 2008, 19 (7-8) :454-492

[3] Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer [J].

Ang, K. Kian ;

Harris, Jonathan ;

Wheeler, Richard ;

Weber, Randal ;

Rosenthal, David I. ;

Nguyen-Tan, Phuc Felix ;

Westra, William H. ;

Chung, Christine H. ;

Jordan, Richard C. ;

Lu, Charles ;

Kim, Harold ;

Axelrod, Rita ;

Silverman, C. Craig ;

Redmond, Kevin P. ;

Gillison, Maura L. .

NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (01) :24-35

[4] Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma [J].

Arroyo, Jason D. ;

Chevillet, John R. ;

Kroh, Evan M. ;

Ruf, Ingrid K. ;

Pritchard, Colin C. ;

Gibson, Donald F. ;

Mitchell, Patrick S. ;

Bennett, Christopher F. ;

Pogosova-Agadjanyan, Era L. ;

Stirewalt, Derek L. ;

Tait, Jonathan F. ;

Tewari, Muneesh .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (12) :5003-5008

[5] Minimal residual disease testing in hematologic malignancies and solid cancer [J].

Ben Lassoued, Amin ;

Nivaggioni, Vanessa ;

Gabert, Jean .

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 2014, 14 (06) :699-712

[6] Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis [J].

Carlevaro-Fita, Joana ;

Lanzos, Andres ;

Feuerbach, Lars ;

Hong, Chen ;

Mas-Ponte, David ;

Pedersen, Jakob Skou ;

Johnson, Rory ;

Abascal, Federico ;

Amin, Samirkumar B. ;

Bader, Gary D. ;

Barenboim, Jonathan ;

Beroukhim, Rameen ;

Bertl, Johanna ;

Boroevich, Keith A. ;

Brunak, Soren ;

Campbell, Peter J. ;

Carlevaro-Fita, Joana ;

Chakravarty, Dimple ;

Chan, Calvin Wing Yiu ;

Chen, Ken ;

Choi, Jung Kyoon ;

Deu-Pons, Jordi ;

Dhingra, Priyanka ;

Diamanti, Klev ;

Feuerbach, Lars ;

Fink, J. Lynn ;

Fonseca, Nuno A. ;

Frigola, Joan ;

Gambacorti-Passerini, Carlo ;

Garsed, Dale W. ;

Gerstein, Mark ;

Getz, Gad ;

Gonzalez-Perez, Abel ;

Guo, Qianyun ;

Gut, Ivo G. ;

Haan, David ;

Hamilton, Mark P. ;

Haradhvala, Nicholas J. ;

Harmanci, Arif O. ;

Helmy, Mohamed ;

Herrmann, Carl ;

Hess, Julian M. ;

Hobolth, Asger ;

Hodzic, Ermin ;

Hong, Chen ;

Hornshoj, Henrik ;

Isaev, Keren ;

Izarzugaza, Jose M. G. ;

Johnson, Todd A. ;

Juul, Malene .

COMMUNICATIONS BIOLOGY, 2020, 3 (01)

[7] Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia [J].

Cavé, H ;

ten Bosch, JV ;

Suciu, S ;

Guidal, C ;

Waterkeyn, C ;

Otten, J ;

Bakkus, M ;

Thielemans, K ;

Grandchamp, B ;

Vilmer, E .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (09) :591-598

[8] MicroRNA based Pan-Cancer Diagnosis and Treatment Recommendation [J].

Cheerla, Nikhil ;

Gevaert, Olivier .

BMC BIOINFORMATICS, 2017, 18

[9] Noncoding human Y RNAs are overexpressed in tumours and required for cell proliferation [J].

Christov, C. P. ;

Trivier, E. ;

Krude, T. .

BRITISH JOURNAL OF CANCER, 2008, 98 (05) :981-988

[10] Functional requirement of noncoding Y RNAs for human chromosomal DNA replication [J].

Christov, Christo P. ;

Gardiner, Timothy J. ;

Szuts, David ;

Krude, Torsten .

MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (18) :6993-7004

← 1 2 3 4 5 6 7 8 9 →