Total synthesis of (±)-FR66979

被引：49

作者：

Ducray, R

Ciufolini, MA ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, UMR 5078, Lab Synthese & Methodol Organ, F-69622 Villeurbanne, France

[2] Ecole Super Chim Phys Elect Lyon, F-69622 Villeurbanne, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2002年 / 41卷 / 24期

关键词：

antitumor agents; asymmetric synthesis; natural products; rearrangement; total synthesis;

D O I：

10.1002/anie.200290017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An unusual fragmentation of aziridine 1, triggered by a preliminary homo-Brook transposition is the key step in the total synthesis of the racemate of the antitumor agent FR66979 (2).

引用

页码：4688 / 4691

页数：4

共 57 条

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