Total synthesis of (±)-FR66979

被引：49
作者：
Ducray, R
Ciufolini, MA [1 ]
机构：
[1] Univ Lyon 1, CNRS, UMR 5078, Lab Synthese & Methodol Organ, F-69622 Villeurbanne, France
[2] Ecole Super Chim Phys Elect Lyon, F-69622 Villeurbanne, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2002年 / 41卷 / 24期
关键词：
antitumor agents; asymmetric synthesis; natural products; rearrangement; total synthesis;
D O I：
10.1002/anie.200290017
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An unusual fragmentation of aziridine 1, triggered by a preliminary homo-Brook transposition is the key step in the total synthesis of the racemate of the antitumor agent FR66979 (2).
引用
收藏
页码：4688 / 4691
页数：4
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