A Prospective Randomized Study to Assess the Efficacy of Rate and Site of Atrial Pacing on Long-Term Development of Atrial Fibrillation

被引：9
作者：
Lau, Chu-Pak [1 ]
Wang, Chun-Chieh [2 ]
Ngarmukos, Tachapong [3 ]
Kim, You-Ho
Kong, Chi-Woon [4 ]
Omar, Razali [5 ]
Sriratanasathavorn, Charn [6 ]
Munawar, Muhammad
Kam, Ruth [7 ]
Lee, Kathy Lf
Lau, Elizabeth Oi-Yan [8 ]
Tse, Hung-Fat
机构：
[1] Univ Hong Kong, Inst Cardiovasc Sci & Med, Queen Mary Hosp, Hong Kong, Hong Kong, Peoples R China
[2] Chang Gung Mem Hosp, Linkou, Taiwan
[3] Mahidol Univ, Ramathibodi Hosp, Bangkok 10700, Thailand
[4] Taipei Vet Gen Hosp, Taipei, Taiwan
[5] Asan Med Ctr, Asan, South Korea
[6] Mahidol Univ, Siriraj Hosp, Bangkok 10700, Thailand
[7] Changi Gen Hosp, Singapore, Singapore
[8] St Jude Med, Hong Kong, Hong Kong, Peoples R China
来源：
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY | 2009年 / 20卷 / 09期
关键词：
atrial fibrillation; atrial overdrive pacing; atrial high rate episode; atrial fibrillation burden; pacemaker; site of atrial pacing; SICK SINUS SYNDROME; TRIAL; PREVENTION; PACEMAKER; TACHYARRHYTHMIAS; SUPPRESSION; BRADYCARDIA; SELECTION; OUTCOMES; RHYTHM;
D O I：
10.1111/j.1540-8167.2009.01484.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The Septal Pacing for Atrial Fibrillation Suppression Evaluation (SAFE) study is a single-blinded, parallel randomized designed multicenter study in pacemaker indicated patients with paroxysmal atrial fibrillation (AF). The objective is to evaluate whether the site of atrial pacing--conventional right atrial appendage versus low atrial septal-with or without atrial overdrive pacing will influence the development of persistent AF. The study will provide a definitive answer to whether a different atrial pacing site or the use of AF suppression pacing or both can give incremental antiarrhythmic benefit when one is implanting a device for a patient with a history of paroxysmal AF. (J Cardiovasc Electrophysiol, Vol. 20, pp. 1020-1025).
引用
收藏
页码：1020 / 1025
页数：6
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