Alashinols F and G, two lignans from stem bark of Syringa pinnatifolia

被引：20

作者：

Feng, Xiao ^{[1
]}

Su, Guozhu ^{[1
]}

Ye, Yunyun ^{[1
,2
]}

Zhang, Ruifei ^{[1
]}

Yang, Xinyao ^{[1
]}

Du, Bingzhao ^{[1
]}

Peng, Bing ^{[3
]}

Tu, Pengfei ^{[1
]}

Chai, Xingyun ^{[1
]}

机构：

[1] Beijing Univ Chinese Med, Modern Res Ctr Tradit Chinese Med, Beijing, Peoples R China

[2] Univ Ningxia Engn & Technol, Res Ctr Modernizat Hui Med, Pharmaceut Sch Ningxia Med, Yinchuan, Peoples R China

[3] Capital Med Univ, Beijing Hosp Tradit Chinese Med, Beijing Inst Tradit Chinese Med, Beijing, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2017年 / 31卷 / 13期

基金：

中国国家自然科学基金;

关键词：

Syringa pinnatifolia; lignan; alashinol F; alashinol G; calculated ECD; CONSTITUENTS;

D O I：

10.1080/14786419.2017.1283500

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new lignans, alashinols F and G (1 and 2), together with two known analogues (-)-secoisolariciresinol (3) and meso-secoisolariciresinol (4) were isolated from the stem bark of Syringa pinnatifolia, a Mongolian folk medicine with anti-myocardial ischaemic effects. Their structures were elucidated on basis of spectroscopic data analyses, including MS and 1D and 2D NMR, and their absolute configurations were elucidated on the basis of experimental and calculated electronic circular dichroisms. The in vitro anti-inflammation and anti-hypoxia evaluations were also discussed.

引用

页码：1555 / 1560

页数：6

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