Esophageal and Esophagogastric Junction Cancers, Version 1.2015

被引：301

作者：

Ajani, Jaffer A. ^{[1
]}

D'Amico, Thomas A.

Almhanna, Khaldoun ^{[2
]}

Bentrem, David J. ^{[3
]}

Besh, Stephen ^{[4
]}

Chao, Joseph ^{[5
]}

Das, Prajnan ^{[1
]}

Denlinger, Crystal ^{[6
]}

Fanta, Paul ^{[7
]}

Fuchs, Charles S. ^{[8
]}

Gerdes, Hans ^{[9
]}

Glasgow, Robert E. ^{[10
]}

Hayman, James A. ^{[11
]}

Hochwald, Steven ^{[12
]}

Hofstetter, Wayne L. ^{[1
]}

Ilson, David H. ^{[9
]}

Jaroszewski, Dawn

Jasperson, Kory ^{[10
]}

Keswani, Rajesh N. ^{[3
]}

Kleinberg, Lawrence R. ^{[13
]}

Korn, W. Michael ^{[14
]}

Leong, Stephen ^{[15
]}

Lockhart, A. Craig ^{[16
,17
]}

Mulcahy, Mary F. ^{[3
]}

Orringer, Mark B. ^{[11
]}

Posey, James A. ^{[18
]}

Poultsides, George A. ^{[19
]}

Sasson, Aaron R.

Scott, Walter J. ^{[6
]}

Strong, Vivian E. ^{[9
]}

Varghese, Thomas K., Jr. ^{[20
]}

Washington, Mary Kay ^{[21
]}

Willett, Christopher G.

Wright, Cameron D. ^{[22
]}

Zelman, Debra

McMillian, Nicole

Sundar, Hema

机构：

[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[2] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[3] NorthWestern Univ, Robert H Lurie Comprehens Canc Ctr, Chicago, IL USA

[4] Univ Tennessee, Hlth Sci Ctr, St Jude Childrens Res Hosp, Knoxville, TN 37996 USA

[5] City Hope Comprehens Canc Ctr, Duarte, CA USA

[6] Fox Chase Canc Ctr, Philadelphia, PA USA

[7] UC San Diego Moores Canc Ctr, La Jolla, CA 92093 USA

[8] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA

[9] Mem Sloan Kettering Canc Ctr, New York, NY 10065 USA

[10] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[11] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[12] Roswell Pk Canc Inst, Buffalo, NY 14263 USA

[13] Sidney Kimmel Comprehens Canc Ctr Johns Hopkins, Sidney, BC, Canada

[14] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[15] Univ Colorado, Ctr Canc, Boulder, CO 80309 USA

[16] Washington Univ, Sch Med, St Louis, MO 63130 USA

[17] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO 63110 USA

[18] Univ Alabama Birmingham, Birmingham, AL 35233 USA

[19] Stanford Canc Inst, Stanford, CA USA

[20] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, Seattle, WA USA

[21] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[22] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2015年 / 13卷 / 02期

基金：

美国国家卫生研究院;

关键词：

PHASE-II TRIAL; POSITRON-EMISSION-TOMOGRAPHY; SQUAMOUS-CELL CARCINOMA; COMBINED-MODALITY THERAPY; DOCETAXEL PLUS CISPLATIN; GASTRIC-CANCER; GASTROESOPHAGEAL JUNCTION; METASTATIC ADENOCARCINOMA; RANDOMIZED-TRIAL; PREOPERATIVE CHEMORADIOTHERAPY;

D O I：

10.6004/jnccn.2015.0028

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Esophageal cancer is the sixth most common cause of cancer deaths worldwide. Adenocarcinoma is more common in North America and Western European countries, originating mostly in the lower third of the esophagus, which often involves the esophagogastric junction (EGJ). Recent randomized trials have shown that the addition of preoperative chemoradiation or perioperative chemotherapy to surgery significantly improves survival in patients with resectable cancer. Targeted therapies with trastuzumab and ramucirumab have produced encouraging results in the treatment of advanced or metastatic EGJ adenocarcinomas. Multidisciplinary team management is essential for patients with esophageal and EGJ cancers. This portion of the NCCN Guidelines for Esophageal and EGJ Cancers discusses management of locally advanced adenocarcinoma of the esophagus and EGJ.

引用

页码：194 / 227

页数：34

共 129 条

[1] Mature Results from a Phase II Trial of Postoperative Concurrent Chemoradiotherapy for Poor Prognosis Cancer of the Esophagus and Gastroesophageal Junction [J].

Adelstein, David J. ;

Rice, Thomas W. ;

Rybicki, Lisa A. ;

Saxton, Jerrold P. ;

Videtic, Gregory M. M. ;

Murthy, Sudish C. ;

Mason, David P. ;

Rodriguez, Cristina P. ;

Ives, Denise I. .

JOURNAL OF THORACIC ONCOLOGY, 2009, 4 (10) :1264-1269

[2] ACTIVITY OF TAXOL IN PATIENTS WITH SQUAMOUS-CELL CARCINOMA AND ADENOCARCINOMA OF THE ESOPHAGUS [J].

AJANI, JA ;

ILSON, DH ;

DAUGHERTY, K ;

PAZDUR, R ;

LYNCH, PM ;

KELSEN, DP .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1994, 86 (14) :1086-1091

[3] Phase II multi-institutional randomized trial of docetaxel plus cisplatin with or without fluorouracil in patients with untreated, advanced gastric, or gastroesophageal adenocarcinoma [J].

Ajani, JA ;

Fodor, MB ;

Tjulandin, SA ;

Moiseyenko, VM ;

Chao, Y ;

Filho, SC ;

Cabral, S ;

Majlis, A ;

Assadourian, S ;

Van Cutsem, E .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (24) :5660-5667

[4] Biweekly fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) for patients with metastatic adenocarcinoma of the stomach or esophagogastric junction: a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie [J].

Al-Batran, S. -E. ;

Hartmann, J. T. ;

Hofheinz, R. ;

Homann, N. ;

Rethwisch, V. ;

Probst, S. ;

Stoehlmacher, J. ;

Clemens, M. R. ;

Mahlberg, R. ;

Fritz, M. ;

Seipelt, G. ;

Sievert, M. ;

Pauligk, C. ;

Atmaca, A. ;

Jaeger, E. .

ANNALS OF ONCOLOGY, 2008, 19 (11) :1882-1887

[5] Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin:: A study of the arbeitsgemeinschaft internistische onkologie [J].

Al-Batran, Salah-Eddin ;

Hartmann, Joerg Thomas ;

Probst, Stephan ;

Schmalenberg, Harald ;

Hollerbach, Stephan ;

Hofheinz, Ralf ;

Rethwisch, Volker ;

Seipelt, Gernot ;

Homann, Nils ;

Wilhelm, Gerhard ;

Schuch, Gunter ;

Stoehlmacher, Jan ;

Derigs, Hans Guenter ;

Hegewisch-Becker, Susanna ;

Grossmann, Johannes ;

Pauligk, Claudia ;

Atmaca, Akin ;

Bokemeyer, Carsten ;

Knuth, Alexander ;

Jaeger, Elke .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (09) :1435-1442

[6] Phase II studies on docetaxel alone every third week, or weekly in combination with gemcitabine in patients with primary locally advanced, metastatic, or recurrent esophageal cancer [J].

Albertsson, M. ;

Johansson, B. ;

Friesland, S. ;

Kadar, L. ;

Letocha, H. ;

Frykholm, G. ;

Wagenius, G. .

MEDICAL ONCOLOGY, 2007, 24 (04) :407-412

[7] Long-Term Results of a Randomized Trial of Surgery With or Without Preoperative Chemotherapy in Esophageal Cancer [J].

Allum, William H. ;

Stenning, Sally P. ;

Bancewicz, John ;

Clark, Peter I. ;

Langley, Ruth E. .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (30) :5062-5067

[8]

[Anonymous], J CLIN ONCOL S15

[9]

[Anonymous], J CLIN ONCOL S15

[10]

[Anonymous], 2009 ASCO GASTR CANC

← 1 2 3 4 5 6 7 8 9 10 →