Role of non-coding regulatory ribonucleic acids in chronic inflammatory diseases

被引:0
作者
Heinz, G. A. [1 ]
Mashreghi, M. -F. [1 ]
机构
[1] Deutsch Rheuma Forschungszentrum DRFZ, Charitepl 1, D-10117 Berlin, Germany
来源
ZEITSCHRIFT FUR RHEUMATOLOGIE | 2016年 / 75卷 / 04期
关键词
MicroRNA; Rheumatoid arthritis; Inflammation; Long non coding RNA; Circular RNA; ARTHRITIS; HOTAIR; RNAS;
D O I
10.1007/s00393-016-0085-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Non-coding regulatory ribonucleic acids (RNA), including microRNA, long non-coding RNA and circular RNA, can influence the expression of genes mediating inflammatory processes and therefore affect the course and progression of chronic inflammatory diseases. Recent studies using antisense oligonucleotides suggest that such non-coding regulatory RNAs are suitable as novel therapeutic target molecules for the treatment of inflammatory rheumatic diseases.
引用
收藏
页码:402 / 405
页数:4
相关论文
共 10 条
  • [1] Essential Role of MicroRNA-155 in the Pathogenesis of Autoimmune Arthritis in Mice
    Blueml, Stephan
    Bonelli, Michael
    Niederreiter, Birgit
    Puchner, Antonia
    Mayr, Georg
    Hayer, Silvia
    Koenders, Marije I.
    van den Berg, Wim B.
    Smolen, Josef
    Redlich, Kurt
    [J]. ARTHRITIS AND RHEUMATISM, 2011, 63 (05): : 1281 - 1288
  • [2] Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes
    Ezkurdia, Iakes
    Juan, David
    Manuel Rodriguez, Jose
    Frankish, Adam
    Diekhans, Mark
    Harrow, Jennifer
    Vazquez, Jesus
    Valencia, Alfonso
    Tress, Michael L.
    [J]. HUMAN MOLECULAR GENETICS, 2014, 23 (22) : 5866 - 5878
  • [3] Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
    Gupta, Rajnish A.
    Shah, Nilay
    Wang, Kevin C.
    Kim, Jeewon
    Horlings, Hugo M.
    Wong, David J.
    Tsai, Miao-Chih
    Hung, Tiffany
    Argani, Pedram
    Rinn, John L.
    Wang, Yulei
    Brzoska, Pius
    Kong, Benjamin
    Li, Rui
    West, Robert B.
    van de Vijver, Marc J.
    Sukumar, Saraswati
    Chang, Howard Y.
    [J]. NATURE, 2010, 464 (7291) : 1071 - U148
  • [4] miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim
    Haftmann, Claudia
    Stittrich, Anna-Barbara
    Zimmermann, Jakob
    Fang, Zhuo
    Hradilkova, Kristyna
    Bardua, Markus
    Westendorf, Kerstin
    Heinz, Gitta A.
    Riedel, Rene
    Siede, Julia
    Lehmann, Katrin
    Weinberger, Esther E.
    Zimmel, David
    Lauer, Uta
    Haeupl, Thomas
    Sieper, Joachim
    Backhaus, Marina
    Neumann, Christian
    Hoffmann, Ute
    Porstner, Martina
    Chen, Wei
    Gruen, JoachimR
    Baumgrass, Ria
    Matz, Mareen
    Loehning, Max
    Scheffold, Alexander
    Wittmann, Juergen
    Chang, Hyun-Dong
    Rajewsky, Nikolaus
    Jaeck, Hans-Martin
    Radbruch, Andreas
    Mashreghi, Mir-Farzin
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 2015, 45 (04) : 1192 - 1205
  • [5] Circular RNAs are a large class of animal RNAs with regulatory potency
    Memczak, Sebastian
    Jens, Marvin
    Elefsinioti, Antigoni
    Torti, Francesca
    Krueger, Janna
    Rybak, Agnieszka
    Maier, Luisa
    Mackowiak, Sebastian D.
    Gregersen, Lea H.
    Munschauer, Mathias
    Loewer, Alexander
    Ziebold, Ulrike
    Landthaler, Markus
    Kocks, Christine
    le Noble, Ferdinand
    Rajewsky, Nikolaus
    [J]. NATURE, 2013, 495 (7441) : 333 - 338
  • [6] Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model
    Pandis, Ioannis
    Ospelt, Caroline
    Karagianni, Niki
    Denis, Maria C.
    Reczko, Martin
    Camps, Carme
    Hatzigeorgiou, Artemis G.
    Ragoussis, Jiannis
    Gay, Steffen
    Kollias, George
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (10) : 1716 - 1723
  • [7] Joining the long shots: emerging evidence on the role of long noncoding RNAs in rheumatoid arthritis
    Scaria, Vinod
    [J]. International Journal of Rheumatic Diseases, 2014, 17 (08) : 831 - 833
  • [8] PBMC and exosome-derived Hotair is a critical regulator and potent marker for rheumatoid arthritis
    Song, Jinsoo
    Kim, Dongkyun
    Han, Jiyeon
    Kim, Yunha
    Lee, Myeungsu
    Jin, Eun-Jung
    [J]. CLINICAL AND EXPERIMENTAL MEDICINE, 2015, 15 (01) : 121 - 126
  • [9] Deregulation and therapeutic potential of microRNAs in arthritic diseases
    Vicente, Rita
    Noel, Daniele
    Pers, Yves-Marie
    Apparailly, Florence
    Jorgensen, Christian
    [J]. NATURE REVIEWS RHEUMATOLOGY, 2016, 12 (04) : 211 - 220
  • [10] Long non-coding RNA ANRIL regulates inflammatory responses as a novel component of NF-κB pathway
    Zhou, Xiao
    Han, Xiaorui
    Wittfeldt, Ann
    Sun, Jingzhi
    Liu, Chujun
    Wang, Xiaoxia
    Gan, Li-Ming
    Cao, Huiqing
    Liang, Zicai
    [J]. RNA BIOLOGY, 2016, 13 (01) : 98 - 108