Regulation of the mitochondrial transition pore: impact on mammalian aging

被引:4
作者
Osiewacz, Heinz D. [1 ]
机构
[1] Goethe Univ Frankfurt, Fac Biosci & Cluster Excellence Mol Complexe, Inst Mol Biosci, D-60438 Frankfurt, Germany
来源
AGING-US | 2011年 / 3卷 / 01期
关键词
MODEL PODOSPORA-ANSERINA; CELL-DEATH; APOPTOSIS; STRESS; LIFE; RAT;
D O I
10.18632/aging.100259
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:10 / 11
页数:2
相关论文
共 13 条
[1]   Cyclophilin D links programmed cell death and organismal aging in Podospora anserina [J].
Brust, Diana ;
Daum, Bertram ;
Breunig, Christine ;
Hamann, Andrea ;
Kuehlbrandt, Werner ;
Osiewacz, Heinz D. .
AGING CELL, 2010, 9 (05) :761-775
[2]   Deletion of PaAif2 and PaAmid2, two genes encoding mitochondrial AIF-like oxidoreductases of Podospora anserina, leads to increased stress tolerance and lifespan extension [J].
Brust, Diana ;
Hamann, Andrea ;
Osiewacz, Heinz D. .
CURRENT GENETICS, 2010, 56 (03) :225-235
[3]   Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease [J].
Du, Heng ;
Guo, Lan ;
Fang, Fang ;
Chen, Doris ;
Sosunov, Alexander A. ;
McKhann, Guy M. ;
Yan, Yilin ;
Wang, Chunyu ;
Zhang, Hong ;
Molkentin, Jeffery D. ;
Gunn-Moore, Frank J. ;
Vonsattel, Jean Paul ;
Arancio, Ottavio ;
Chen, John Xi ;
Du Yan, Shi .
NATURE MEDICINE, 2008, 14 (10) :1097-1105
[4]   Differential proteomic profiling of mitochondria from Podospora anserina, rat and human reveals distinct patterns of age-related oxidative changes [J].
Groebe, Karlfried ;
Krause, Frank ;
Kunstmann, Birgit ;
Unterluggauer, Hermann ;
Relfschneider, Nicole H. ;
Scheckhuber, Christian Q. ;
Sastri, Charturvedala ;
Stegmann, Werner ;
Wozny, Wojciech ;
Schwall, Gerhard P. ;
Poznanovic, Slobodan ;
Dencher, Norbert A. ;
Jansen-Duerr, Pidder ;
Osiewacz, Heinz D. ;
Schrattenholz, Andre .
EXPERIMENTAL GERONTOLOGY, 2007, 42 (09) :887-898
[5]   Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy [J].
Hafner, Angela V. ;
Dai, Jing ;
Gomes, Ana P. ;
Xiao, Chun-Yang ;
Palmeira, K. Carlos M. ;
Rosenzweig, Anthony ;
Sinclair, David A. .
AGING-US, 2010, 2 (12) :914-923
[6]   Deletion of putative apoptosis factors leads to lifespan extension in the fungal ageing model Podospora anserina [J].
Hamann, Andrea ;
Brust, Diana ;
Osiewacz, Heinz D. .
MOLECULAR MICROBIOLOGY, 2007, 65 (04) :948-958
[7]   Mitochondrial membrane permeabilization in cell death [J].
Kroemer, Guido ;
Galluzzi, Lorenzo ;
Brenner, Catherine .
PHYSIOLOGICAL REVIEWS, 2007, 87 (01) :99-163
[8]   Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging [J].
Kujoth, GC ;
Hiona, A ;
Pugh, TD ;
Someya, S ;
Panzer, K ;
Wohlgemuth, SE ;
Hofer, T ;
Seo, AY ;
Sullivan, R ;
Jobling, WA ;
Morrow, JD ;
Van Remmen, H ;
Sedivy, JM ;
Yamasoba, T ;
Tanokura, M ;
Weindruch, R ;
Leeuwenburgh, C ;
Prolla, TA .
SCIENCE, 2005, 309 (5733) :481-484
[9]   Age-related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle [J].
Marzetti, Emanuele ;
Wohlgemuth, Stephanie Eva ;
Lees, Hazel Anne ;
Chung, Hae-Young ;
Giovannini, Silvia ;
Leeuwenburgh, Christiaan .
MECHANISMS OF AGEING AND DEVELOPMENT, 2008, 129 (09) :542-549
[10]   Aging in fungi:: role of mitochondria in Podospora anserina [J].
Osiewacz, HD .
MECHANISMS OF AGEING AND DEVELOPMENT, 2002, 123 (07) :755-764