Change in Alcohol Use Based on Self-Report and a Quantitative Biomarker, Phosphatidylethanol, in People With HIV

被引：4

作者：

McGinnis, Kathleen A. ^{[1
]}

Tate, Janet P. ^{[1
,2
]}

Bryant, Kendall J. ^{[3
]}

Justice, Amy C. ^{[1
,2
]}

O'Connor, Patrick G. ^{[2
]}

Rodriguez-Barradas, Maria C. ^{[4
,5
]}

Crystal, Stephen ^{[6
]}

Cutter, Christopher J. ^{[2
]}

Hansen, Nathan B. ^{[7
]}

Maisto, Stephen A. ^{[8
]}

Marconi, Vincent C. ^{[9
,10
,11
]}

Williams, Emily C. ^{[12
,13
]}

Cook, Robert L. ^{[14
]}

Gordon, Adam J. ^{[15
,16
]}

Gordon, Kirsha S. ^{[1
,2
]}

Eyawo, Oghenowede ^{[17
]}

Edelman, E. Jennifer ^{[2
,18
]}

Fiellin, David A. ^{[2
]}

机构：

[1] US Dept Vet Affairs, VA Connecticut Healthcare Syst, West Haven, CT 06516 USA

[2] Yale Sch Med, New Haven, CT USA

[3] Natl Inst Alcohol Abuse & Alcoholism, Bethesda, MD USA

[4] Baylor Coll Med, Michael E DeBakey VAMC, Infect Dis Sect, Houston, TX 77030 USA

[5] Baylor Coll Med, Dept Med, Houston, TX 77030 USA

[6] Rutgers State Univ, Inst Hlth Hlth Care Policy & Aging Res, New Brunswick, NJ USA

[7] Univ Georgia, Coll Publ Hlth, Athens, GA 30602 USA

[8] Syracuse Univ, Dept Psychol, Syracuse, NY USA

[9] Emory Univ, Sch Med, Atlanta, GA 30322 USA

[10] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA

[11] Atlanta Vet Affairs Med Ctr, Decatur, GA USA

[12] Univ Washington, Sch Publ Hlth, Dept Hlth Syst & Populat, Seattle, WA 98195 USA

[13] VA Puget Sound Healthcare Syst, Seattle Denver Hlth Serv Res Sr Dev Ctr Innovat V, Seattle, WA USA

[14] Univ Florida, Dept Epidemiol, Gainesville, FL USA

[15] Univ Utah, Salt Lake City, UT USA

[16] Salt Lake City VA Hlth Care Syst, Salt Lake City, UT USA

[17] York Univ, Sch Global Hlth, Toronto, ON, Canada

[18] Yale Sch Publ Hlth, Ctr Interdisciplinary Res AIDS, New Haven, CT USA

来源：

AIDS AND BEHAVIOR | 2022年 / 26卷 / 03期

基金：

美国国家卫生研究院;

关键词：

Alcohol consumption; Phosphatidylethanolamine; HIV infection; DISORDERS IDENTIFICATION TEST; INTERACTIVE TOXICITY BELIEFS; AUDIT-C; CONSUMPTION; BLOOD; PETH; INFECTION; DISEASE; MARKER; VALIDATION;

D O I：

10.1007/s10461-021-03438-y

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The timeline followback (TLFB) takes more resources to collect than the Alcohol Use Disorder Identification Test (AUDIT-C). We assessed agreement of TLFB and AUDIT-C with the biomarker phosphatidylethanol (PEth) and compared changes in TLFB and PEth among persons with HIV (PWH) using secondary data from randomized trials. We calculated operating characteristics and agreement between TLFB (> 1 and > 2 average drinks/day), AUDIT-C >= 4 and PEth >= 20 among 275 men with HIV. Median age was 57 years, 80% were African-American; and 17% white. Sixty-eight percent had PEth >= 20, 46% reported > 2 average drinks/day on TLFB, 61% reported > 1 average drinks/day on TLFB, and 72% had an AUDIT-C >= 4. Relative to PEth, sensitivity for AUDIT-C >= 4 was 84% (kappa = 0.36), and for TLFB > 1 average drink/day was 76% (kappa = 0.44). Change in alcohol use appeared greater using TLFB measures than PEth. Strategies to robustly assess alcohol use in PWH may require both self-report and biomarkers.

引用

页码：786 / 794

页数：9

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