Precision medicine for advanced colorectal and gastroesophageal cancer

被引：0

作者：

Miguel Reyes, Jose ^{[1
]}

机构：

[1] Clin Las Condes, Ctr Canc Maria Luisa Solari Falabella, Dept Oncol Med, Santiago, Chile

来源：

REVISTA MEDICA CLINICA LAS CONDES | 2022年 / 33卷 / 02期

关键词：

Esophageal Cancers; Gastric Cancer; Neoplasma; KRAS WILD-TYPE; OPEN-LABEL; 1ST-LINE TREATMENT; PHASE-III; FLUOROURACIL FAILURE; CONTINUOUS-INFUSION; 2ND-LINE TREATMENT; PLUS CHEMOTHERAPY; RANDOMIZED-TRIAL; GASTRIC-CANCER;

D O I：

10.1016/j.rmclc.2022.03.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Colorectal and gastroesophageal cancer have a global high incidence and a high mortality rate. Surgery persists as the only curative therapy for patients with early stages of both diseases. In those patients that are diagnosed with metastatic or unresectable cancer, or that become metastatic after locoregional treatment, chemotherapy has been the traditional therapy, with rather poor results in terms of survival or progression free survival. Precision medicine using molecular markers is changing this situation. Herein we review the most relevant aspects with regards to advances in the treatment of both diseases.

引用

页码：125 / 139

页数：15

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