Chronic skin lichenification as an unusual presentation of eosinophilic granulomatosis with polyangiitis: case report and literature review

被引：0
作者：
Sbrana, F. [1 ]
Loggini, B. [2 ]
Galimberti, S. [3 ]
Coceani, M. [1 ]
Latorre, M. [4 ]
Seccia, V [5 ]
L'Abbate, S. [6 ]
Mosca, M. [6 ]
Pasanisi, E. M. [1 ]
Baldini, C. [6 ]
机构：
[1] Fdn Toscana Cabriele Monasterio, Pisa, Italy
[2] Univ Pisa, Inst Pathol Anat, I-56100 Pisa, Italy
[3] Univ Pisa, Dept Oncol Transplants & New Med Tech, Hematol Unit, I-56100 Pisa, Italy
[4] Univ Pisa, Cardio Thorac & Vasc Dept, I-56100 Pisa, Italy
[5] Azienda Osped Univ Pisana, Ear Nose Throat Unit 1, Rome, Italy
[6] Univ Pisa, UO Rheumatol, Dept Internal Med, I-56100 Pisa, Italy
来源：
ACTA REUMATOLOGICA PORTUGUESA | 2016年 / 41卷 / 02期
关键词：
Chronic skin lichenification; Eosinophilic; Granulomatosis with Polyangiitis; Hypereosinophilic syndrome; CHURG-STRAUSS-SYNDROME; RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS; ALLERGIC GRANULOMATOSIS; BLOOD EOSINOPHILIA; LIMITED FORM; ANGIITIS; CLASSIFICATION; ASTHMA; MASS;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Eosinophilic granulomatosis with polyangiitis (EGPA) is an uncommon ANCA-associated systemic small-vessel necrotizing vasculitis. At times, EGPA presenting manifestations can be very different from the usually recognized disease patterns. We report a 52-year-old female patient with 3 years history of itching. In this period, the patient developed chronic skin lichenification on her legs followed by full-blown ANCA-MPO positive EGPA in combination with blood hypereosinophilia, eosinophilic vasculitis at skin biopsy, subclinical asthma and chronic rhinosinusitis.
引用
收藏
页码：158 / 161
页数：4
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