Macrocycles as a Tool: A Facile and One-Pot Synthesis of Silver Nanoparticles Using Cucurbituril Designed for Cancer Therapeutics

被引：52
作者：
Premkumar, Thathan [1 ]
Lee, Yeonju [1 ]
Geckeler, Kurt E. [1 ,2 ]
机构：
[1] GIST, Dept Mat Sci & Engn, Kwangju 500712, South Korea
[2] World Class Univ, Dept Nanobio Mat & Elect, GIST, Kwangju 500712, South Korea
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 38期
关键词：
biomedical applications; cucurbiturils; cytotoxicity; nanoparticles; silver;
D O I：
10.1002/chem.201001325
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Silver nanoparticles made easy: A simple, effective, and one-pot method toward the synthesis of a defined macrocycle-silver nanoparticle system in water has been described (see figure). Interestingly, cucurbituril (CB)[7]-protected AgNPs showed significantly increased cytotoxicity against MCF-7 and NCI-H358 cancer cells, as demonstrated by models in vitro. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：11563 / 11566
页数：4
相关论文
共 20 条
  • [1] A general and efficient method to form self-assembled cucurbit[n]uril monolayers on gold surfacest
    An, Qi
    Li, Guangtao
    Tao, Chengan
    Li, Yan
    Wu, Yiguang
    Zhang, Weixia
    [J]. CHEMICAL COMMUNICATIONS, 2008, (17) : 1989 - 1991
  • [2] [Anonymous], 2005, ANGEW CHEM, DOI DOI 10.1002/ANIE.201210267
  • [3] Gold nanoparticles in organic capsules:: A supramolecular assembly of gold nanoparticles and cucurbituril
    Corma, Avelino
    Garcia, Hermenegildo
    Montes-Navajas, Pedro
    Primo, Ana
    Calvino, Jose Juan
    Trasobares, Susana
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (22) : 6359 - 6364
  • [4] Solid-State Synthesis of Silver Nanoparticles at Room Temperature: Poly(vinylpyrrolidone) as a Tool
    Debnath, Dipen
    Kim, Chorong
    Kim, Sung H.
    Geckeler, Kurt E.
    [J]. MACROMOLECULAR RAPID COMMUNICATIONS, 2010, 31 (06) : 549 - 553
  • [5] Geckeler K.E., 2003, ADV MACROMOLECULAR S
  • [6] Geckeler KurtE., 2006, FUNCTIONAL NANOMATER
  • [7] A facile synthetic route to aqueous dispersions of silver nanoparticles
    Hasell, Tom
    Yang, Jixin
    Wang, Wenxin
    Brown, Paul D.
    Howdle, Steven M.
    [J]. MATERIALS LETTERS, 2007, 61 (27) : 4906 - 4910
  • [8] Supramolecular nanoencapsulation as a tool:: Solubilization of the anticancer drug trans-dichloro(dipyridine)platinum(II) by complexation with β-cyclodextrin
    Horvath, Gabriela
    Premkumar, Thathan
    Boztas, Ali
    Lee, Eunhye
    Jon, Sangyong
    Geckeler, Kurt E.
    [J]. MOLECULAR PHARMACEUTICS, 2008, 5 (02) : 358 - 363
  • [9] Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils
    Kemp, Sharon
    Wheate, Nial J.
    Wang, Shaoyu
    Collins, J. Grant
    Ralph, Stephen F.
    Day, Anthony I.
    Higgins, Vincent J.
    Aldrich-Wright, Janice R.
    [J]. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2007, 12 (07): : 969 - 979
  • [10] Hole-doped single-walled carbon nanotubes: Ornamenting with gold nanoparticles in water
    Kim, DS
    Lee, T
    Geckeler, KE
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (01) : 104 - 107
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