HKGreen-3: A Rhodol-Based Fluorescent Probe for Peroxynitrite

被引:133
|
作者
Peng, Tao
Yang, Dan [1 ]
机构
[1] Univ Hong Kong, Morningside Lab Chem Biol, Hong Kong, Hong Kong, Peoples R China
关键词
NITRIC-OXIDE; MACROPHAGES; BIOLOGY; CELLS;
D O I
10.1021/ol102182j
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel fluorescent probe, HKGreen-3, for sensing peroxynitrite is designed on the basis of the rhodol scaffold and a peroxynitrite-specific oxidation reaction. The probe turns out to be highly sensitive and selective for detecting peroxynitrite in both chemical and biological systems.
引用
收藏
页码:4932 / 4935
页数:4
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