Effects of depression and anxiety on mortality and quality-of-life 4 months after myocardial infarction

被引:122
作者
Lane, D
Carroll, D [1 ]
Ring, C
Beevers, DG
Lip, GYH
机构
[1] Univ Birmingham, Sch Sport & Exercise Sci, Birmingham B15 2TT, W Midlands, England
[2] Univ Birmingham, City Hosp NHS Trust, Dept Med, Birmingham B18 7QH, W Midlands, England
关键词
depression; anxiety; myocardial infarction; mortality; quality-of-life;
D O I
10.1016/S0022-3999(00)00170-7
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: The purpose of this study was to determine the impact of depression and anxiety on mortality and quality-of-life in patients hospitalized for an acute myocardial infarction (MI). Methods: Questionnaire measures of depression and anxiety were completed during hospitalization by 288 MI patients. The main outcomes were mortality and quality-of-life, assessed by the Dartmouth COOP charts, at 4 months. Results: A total of 25 patients died, 22 from cardiac causes, during the 4-month followup. Symptoms of depression and anxiety did not predict either cardiac or all-cause mortality. Severity of infarction, extent of heart failure, and a longer stay in hospital predicted mortality. Symptoms of depression and anxiety predicted 4-month quality-of-life among survivors, as did gender, partner status, occupational status, living alone, previous exercise behaviour, length of hospital admission, and Peel Index scores. In a multiple regression model, depression emerged as the strongest predictor of quality-of-life. State anxiety, severity of infarction, and partner status also entered the model. Conclusion: Neither depression nor anxiety predicted mortality 4 months after MI. Both depression and anxiety predicted quality-of-life at 4 months among survivors. (C) 2000 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:229 / 238
页数:10
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