Pemphigus vulgaris treated with allogeneic hematopoietic stem cell transplantation following non-myeloablative conditioning

被引：3

作者：

Suslova, I. M. ^{[1
]}

Theodoropoulos, D. S. ^{[2
,3
]}

Cullen, N. A. M. ^{[3
]}

Tetarnikova, M. K.

Tetarnikov, A. S.

Kolchak, N. A. ^{[1
]}

机构：

[1] Omsk State Med Acad, Dept Hematol Oncol, Omsk, Russia

[2] Allergy Associates La Crosse & Fransiscan Skemp H, La Crosse, WI USA

[3] Inst Med Immunol, Volos, Greece

来源：

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | 2010年 / 14卷 / 09期

关键词：

Pemphigus; Hernatopoietic stem cell transplantation; HSCT; Autoimmune diseases; T-CELLS; RAPAMYCIN; FOLIACEUS; DISEASE;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Objectives: Successful treatment of severe, refractory Pemphigus vulgaris (PV) is reported. Methods: Reduced intensity, non-myeloablative conditioning was employed, followed by allogeneic hematopoietic stem cell transplantation (HSCT) from a fully matched sibling. Results: Treatment of refractory PV with myeloablation and subsequent allogenic HSCT has been previously reported, and sustained remission with this approach has been achieved. Toxicity, however, related to condition regimens remains high. Conclusion: Since no cytotoxic chemotherapy was used, it is hereby hypothesized that clinical improvement may result from regulatory action from the donor's marrow: a "graft modifying the disease" effect, which may prove useful in the management of autoimmune diseases.

引用

页码：785 / 788

页数：4

共 50 条

[41] Significance of graft quality in allogeneic hematopoietic stem cell transplantation [J].

Jinca, Cristian ;

Arghirescu, Smaranda ;

Oprisoni, Andrada ;

Balint-Gib, Loredana ;

Baica, Mihaela ;

Serban, Margit .

REVISTA ROMANA DE MEDICINA DE LABORATOR, 2009, 16 (03) :21-27

[42] Allogeneic hematopoietic stem cell transplantation for metastatic breast cancer [J].

Bishop, MR .

HAEMATOLOGICA, 2004, 89 (05) :599-605

[43] Allogeneic Hematopoietic Stem Cell Transplantation for Leukocyte Adhesion Deficiency [J].

Horikoshi, Yasuo ;

Umeda, Katsutsugu ;

Imai, Kohsuke ;

Yabe, Hiromasa ;

Sasahara, Yoji ;

Watanabe, Kenichiro ;

Ozawa, Yukiyasu ;

Hashii, Yoshiko ;

Kurosawa, Hidemitsu ;

Nonoyama, Shigeaki ;

Morio, Tomohiro .

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2018, 40 (02) :137-140

[44] Pleuroparenchymal fibroelastosis after allogeneic hematopoietic stem cell transplantation [J].

Bondeelle, Louise ;

Gras, Julien ;

Michonneau, David ;

Houdouin, Veronique ;

Hermet, Eric ;

Blin, Nicolas ;

Nicolini, Franck ;

Michallet, Mauricette ;

Dominique, Stephane ;

Huynh, Anne ;

Leroy, Sylvie ;

Socie, Gerard ;

Thabut, Gabriel ;

Reynaud-Gaubert, Martine ;

Tazi, Abdellatif ;

Bergeron, Anne .

BONE MARROW TRANSPLANTATION, 2020, 55 (05) :982-986

[45] Ocular Findings after Allogeneic Hematopoietic Stem Cell Transplantation [J].

Tabbara, Khalid F. ;

Al-Ghamdi, Ahmad ;

Al-Mohareb, Fahad ;

Ayas, Mouhab ;

Chaudhri, Naeem ;

Al-Sharif, Fahad ;

Al-Zahrani, Hazzaa ;

Mohammed, Said Y. ;

Nassar, Amr ;

Aljurf, Mahmoud .

OPHTHALMOLOGY, 2009, 116 (09) :1624-1629

[46] Reduced-Intensity Conditioning with Busulfan and Fludarabine for Allogeneic Hematopoietic Stem Cell Transplantation in Acute Lymphoblastic Leukemia [J].

Lee, Seung-Shin ;

Jung, Sung-Hoon ;

Do, Young Rok ;

Kim, Dae Sik ;

Lee, Ji Hyun ;

Park, Han-Seung ;

Moon, Joon Ho ;

Yi, Jun Ho ;

Park, Yong ;

Koh, Youngil ;

Yhim, Ho-Young ;

Choi, Yunsuk ;

Mun, Yeung-Chul ;

Lee, Won-Sik ;

Lee, Seok ;

Yang, Deok-Hwan .

YONSEI MEDICAL JOURNAL, 2020, 61 (06) :452-459

[47] Viral kinetics and outcomes of adenovirus viremia following allogeneic hematopoietic cell transplantation [J].

Chandorkar, Aditya ;

Anderson, Anthony D. ;

Morris, Michele, I ;

Natori, Yoichiro ;

Jimenez, Antonio ;

Komanduri, Krishna, V ;

Camargo, Jose F. .

CLINICAL TRANSPLANTATION, 2021, 35 (12)

[48] Treosulfan-fludarabine-thiotepa-based conditioning treatment before allogeneic hematopoietic stem cell transplantation for pediatric patients with hematological malignancies [J].

Kalwak, Krzysztof ;

Mielcarek, Monika ;

Patrick, Katharine ;

Styczynski, Jan ;

Bader, Peter ;

Corbacioglu, Selim ;

Burkhardt, Birgit ;

Sykora, Karl Walter ;

Drabko, Katarzyna ;

Gozdzik, Jolanta ;

Fagioli, Franca ;

Greil, Johann ;

Gruhn, Bernd ;

Beier, Rita ;

Locatelli, Franco ;

Mueller, Ingo ;

Schlegel, Paul Gerhardt ;

Sedlacek, Petr ;

Stachel, Klaus Daniel ;

Hemmelmann, Claudia ;

Moeller, Ann-Kristin ;

Baumgart, Joachim ;

Vora, Ajay .

BONE MARROW TRANSPLANTATION, 2020, 55 (10) :1996-2007

[49] Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study [J].

Burt, Richard K. ;

Loh, Yvonne ;

Cohen, Bruce ;

Stefosky, Dusan ;

Balabanov, Roumen ;

Katsamakis, George ;

Oyama, Yu ;

Russell, Eric J. ;

Stern, Jessica ;

Muraro, Paolo ;

Rose, John ;

Testori, Alessandro ;

Bucha, Jurate ;

Jovanovic, Borko ;

Milanetti, Francesca ;

Storek, Jan ;

Voltarelli, Julio C. ;

Burns, William H. .

LANCET NEUROLOGY, 2009, 8 (03) :244-253

[50] Severe thrombocytopenia due to host-derived anti-HPA-1a after non-myeloablative allogeneic haematopoietic stem cell transplantation for multiple myeloma: a case report [J].

Macher, S ;

Schallmoser, K ;

Staber, PB ;

Neumeister, P ;

Posch, U ;

Lanzer, G ;

Panzer, S .

VOX SANGUINIS, 2005, 89 (04) :257-260

← 1 2 3 4 5 →