A method for preparing C-glycosides related to phlorizin

被引:47
|
作者
Link, JT [1 ]
Sorensen, BK [1 ]
机构
[1] Abbott Labs, Abbott Pk, IL 60064 USA
关键词
D O I
10.1016/S0040-4039(00)01709-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Johnson's Suzuki coupling protocol was employed to prepare C-glycoside analogs of phlorizin (1). In vitro biological evaluation of these C-glycosides indicated the anomeric oxygen is important to the SGLT inhibitory activity of phlorizin (1) and related agents, (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:9213 / 9217
页数:5
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