Immune Response to Haemophilus influenzae Type b Vaccination in Patients with Chronic Renal Failure

被引:15
作者
Hawdon, Nicole [1 ]
Nix, Eli B. [1 ]
Tsang, Raymond S. W. [2 ]
Ferroni, Garry [1 ]
McCready, William G. [1 ]
Ulanova, Marina [1 ]
机构
[1] Lakehead Univ, No Ontario Sch Med, Thunder Bay, ON P7B 5E1, Canada
[2] Publ Hlth Agcy Canada, Natl Microbiol Lab, Vaccine Preventable Bacterial Dis, Winnipeg, MB, Canada
关键词
CHRONIC KIDNEY-DISEASE; ANTIBODY-RESPONSE; UNITED-KINGDOM; HEPATITIS-B; CONJUGATE; IMMUNOGENICITY; POLYSACCHARIDE; IGM;
D O I
10.1128/CVI.00101-12
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Adult chronic renal failure patients undergoing hemodialysis are at an increased risk of invasive Haemophilus influenzae type b (Hib) disease due to the lack of functionally active anti-Hib antibodies. The pediatric Hib polysaccharide-protein conjugate vaccine is highly immunogenic in these patients and can provide protection against invasive Hib infection for at least 1 year.
引用
收藏
页码:967 / 969
页数:3
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