A PENELOPE-based system for the automated Monte Carlo simulation of clinacs and voxelized geometries-application to far-from-axis fields

被引:220
作者
Sempau, Josep [1 ]
Badal, Andreu [2 ]
Brualla, Lorenzo [3 ]
机构
[1] Univ Politecn Cataluna, Inst Tecn Energet, E-08028 Barcelona, Spain
[2] CDRH US Food & Drug Adm, Div Imaging & Appl Math, OSEL, Silver Spring, MD 20993 USA
[3] Univ Klinikum Essen, Strahlenklin, NCTeam, D-45122 Essen, Germany
关键词
PENELOPE; PENEASY; PENEASYLINAC; voxelized geometry; ELECTRON-TRANSPORT; PHOTON; REDUCTION; VARIANCE; BEAMS; CODE;
D O I
10.1118/1.3643029
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: Two new codes, PENEASY and PENEASYLINAC, which automate the Monte Carlo simulation of Varian Clinacs of the 600, 1800, 2100, and 2300 series, together with their electron applicators and multileaf collimators, are introduced. The challenging case of a relatively small and far-from-axis field has been studied with these tools. Methods: PENEASY is a modular, general-purpose main program for the PENELOPE Monte Carlo system that includes various source models, tallies and variance-reduction techniques (VRT). The code includes a new geometry model that allows the superposition of voxels and objects limited by quadric surfaces. A variant of the VRT known as particle splitting, called fan splitting, is also introduced. PENEASYLINAC, in turn, automatically generates detailed geometry and configuration files to simulate linacs with PENEASY. These tools are applied to the generation of phase-space files, and of the corresponding absorbed dose distributions in water, for two 6 MV photon beams from a Varian Clinac 2100 C/D: a 40 x 40 cm(2) centered field; and a 3 x 5 cm(2) field centered at (4.5, -11.5) cm from the beam central axis. This latter configuration implies the largest possible over-traveling values of two of the jaws. Simulation results for the depth dose and lateral profiles at various depths are compared, by using the gamma index, with experimental values obtained with a PTW 31002 ionization chamber. The contribution of several VRTs to the computing speed of the more demanding off-axis case is analyzed. Results: For the 40 x 40 cm(2) field, the percentages gamma(1) and gamma(1.2) of voxels with gamma indices (using 0.2 cm and 2% criteria) larger than unity and larger than 1.2 are 0.2% and 0%, respectively. For the 3 x 5 cm(2) field, gamma(1) = 0%. These figures indicate an excellent agreement between simulation and experiment. The dose distribution for the off-axis case with voxels of 2.5 x 2.5 x 2.5 mm(3) and an average standard statistical uncertainty of 2% (1 sigma) is computed in 3.1 h on a single core of a 2.8 GHz Intel Core 2 Duo processor. This result is obtained with the optimal combination of the tested VRTs. In particular, fan splitting for the off-axis case accelerates execution by a factor of 240 with respect to standard particle splitting. Conclusions: PENEASY and PENEASYLINAC can simulate the considered Varian Clinacs both in an accurate and efficient manner. Fan splitting is crucial to achieve simulation results for the off-axis field in an affordable amount of CPU time. Work to include Elekta linacs and to develop a graphical interface that will facilitate user input is underway. (C) 2011 American Association of Physicists in Medicine. [DOI: 10.1118/1.3643029]
引用
收藏
页码:5887 / 5895
页数:9
相关论文
共 39 条
  • [1] A new formalism for reference dosimetry of small and nonstandard fields
    Alfonso, R.
    Andreo, P.
    Capote, R.
    Huq, M. Saiful
    Kilby, W.
    Kjaell, P.
    Mackie, T. R.
    Palmans, H.
    Rosser, K.
    Seuntjens, J.
    Ullrich, W.
    Vatnitsky, S.
    [J]. MEDICAL PHYSICS, 2008, 35 (11) : 5179 - 5186
  • [2] Amanatides J., 1987, EUROGRAPHICS, P3, DOI DOI 10.2312/EGTP.19871000
  • [3] Andreo P, 2000, 398 TRS INT AT EN AG
  • [4] [Anonymous], 1984, 37 ICRU
  • [5] A package of Linux scripts for the parallelization of Monte Carlo simulations
    Badal, Andreu
    Sempau, Josep
    [J]. COMPUTER PHYSICS COMMUNICATIONS, 2006, 175 (06) : 440 - 450
  • [6] Bielajew A.F., 1988, MONTE CARLO TRANSPOR, P407
  • [7] On the efficiency of azimuthal and rotational splitting for Monte Carlo simulation of clinical linear accelerators
    Brualla, L.
    Sauerwein, W.
    [J]. RADIATION PHYSICS AND CHEMISTRY, 2010, 79 (09) : 929 - 932
  • [8] Efficient Monte Carlo simulation of multileaf collimators using geometry-related variance-reduction techniques
    Brualla, L.
    Salvat, F.
    Palanco-Zamora, R.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (13) : 4131 - 4149
  • [9] Azimuthal particle redistribution for the reduction of latent phase-space variance in Monte Carlo simulations
    Bush, K.
    Zavgorodni, S. F.
    Beckham, W. A.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2007, 52 (14) : 4345 - 4360
  • [10] Capote R, 2006, INDCNDS0484 INT AT E