Operating on placental support: The ex utero intrapartum treatment procedure

被引:216
作者
Mychaliska, GB
Bealer, JF
Graf, JL
Rosen, MA
Adzick, NS
Harrison, MR
机构
[1] UNIV CALIF SAN FRANCISCO,FETAL TREATMENT CTR,DIV PEDIAT SURG,DEPT SURG,SAN FRANCISCO,CA 94143
[2] UNIV CALIF SAN FRANCISCO,DEPT ANESTHESIA,SAN FRANCISCO,CA 94143
[3] UNIV CALIF SAN FRANCISCO,DEPT OBSTET GYNECOL & REPROD SCI,SAN FRANCISCO,CA 94143
关键词
airway obstruction; congenital diaphragmatic hernia; cystic hygroma; tracheal occlusion;
D O I
10.1016/S0022-3468(97)90184-6
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
While treating eight fetuses with predictable airway obstruction, the authors developed a systematic approach, the ex utero intrapartum treatment procedure, to secure the airway during delivery Six patients had their trachea plugged or clipped in utero for treatment of congenital diaphragmatic hernia, and two patients had prenatally diagnosed cystic hygroma of the neck and oropharynx. The ex utero intrapartum treatment procedure was performed by using high doses of inhaled halogenated agents to facilitate uterine relaxation during cesarean section, securing the fetal airway while fete-placental circulation remained intact, and then dividing the umbilical cord. A variety of procedures were performed during the ex utero intrapartum treatment procedure including bronchoscopy, orotracheal intubation, tracheostomy, tracheostomy with retrograde orotracheal intubation,tracheoplasty, removal of internal tracheal plug, removal of external tracheal clip, central line placement, and instillation of surfactant. There were minimal maternal or fetal complications during the procedure. This approach requires the coordinated efforts of pediatric surgeons, obstetricians, anesthesiologists, sonographers, and neonatologists. The combination of intensive maternal-fetal monitoring, cesarean section with maximal uterine relaxation, and maintenance of intact fete-placental circulation provides a controlled environment for securing the airway in babies with prenatally diagnosed airway obstruction. Copyright (C) 1997 by W.B. Saunders Company.
引用
收藏
页码:227 / 231
页数:5
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