Poly-xanthurenic acid modified electrodes: An amperometric sensor for the simultaneous determination of ascorbic and uric acids

被引：31

作者：

dos Santos Silva, Francisco de Assis ^{[1
,4
]}

Lopes, Cleylton Bezerra ^{[1
,2
,4
]}

Kubota, Lauro Tatsuo ^{[3
,4
]}

Lima, Phabyanno Rodrigues ^{[1
,2
,4
]}

Fonseca Goulart, Marilia Oliveira ^{[1
,4
]}

机构：

[1] Univ Fed Alagoas, Inst Quim & Biotecnol, BR-57072970 Maceio, AL, Brazil

[2] IFAL, Inst Fed Educ Ciencia & Tecnol Alagoas, BR-57020600 Maceio, AL, Brazil

[3] Univ Estadual Campinas, Inst Quim, BR-13084971 Campinas, SP, Brazil

[4] Univ Estadual Campinas, Inst Nacl Ciencia & Tecnol Bioanalit, BR-13084971 Campinas, SP, Brazil

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2012年 / 168卷

关键词：

Xanthurenic acid; MWCNT; Ascorbic acid; Uric acid; Electrocatalysis; Chemically modified electrodes; WALL CARBON NANOTUBES; ELECTROCATALYTIC OXIDATION; PASTE ELECTRODE; HOMOCYSTEINE; DISPERSION; NADH;

D O I：

10.1016/j.snb.2012.04.025

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The poly-xanthurenic acid (poly-Xa)/multi-walled carbon nanotube (MWCNT)/glassy carbon modified electrode (poly-Xa/MWCNT/GCE) was successfully applied for the simultaneous determination of ascorbic (AA) and uric (UA) acids. Cyclic voltammetric results show that the modified electrode displays an excellent eletrocatalytic activity toward the oxidation of AA at a low potential (0.05 V versus Ag/AgCl) and anodic peak resolution (Delta E-pa), close to 300 mV versus Ag/AgCl, in solutions containing AA and UA. Values in the order of 10(6) L mol(-1) s(-1) were obtained for the kinetic constant k(cat) for the catalytic oxidation of AA, upon evaluation by cyclic voltammetry, chronoamperometry and RDE. Furthermore, the sensor provided limits of detection of 0.19 mu mol L-1 and 0.31 mu mol L-1 for AA and UA, respectively. The sensor was applied for the simultaneous determination of AA and UA in urine samples and the average recoveries for these samples were 99.9 (+/-2.5)% and 99.9 (+/-2.6)%, respectively. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：289 / 296

页数：8

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