Ruthenium Catalyzed Synthesis of Enaminones

被引：60

作者：

Koduri, Naga Durgarao ^{[1
]}

Scott, Halee ^{[1
]}

Hileman, Bethany ^{[1
]}

Cox, Justin D. ^{[1
]}

Coffin, Michael ^{[1
]}

Glicksberg, Lindsay ^{[1
]}

Hussaini, Syed R. ^{[1
]}

机构：

[1] Univ Tulsa, Dept Chem & Biochem, Tulsa, OK 74101 USA

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 02期

基金：

美国国家科学基金会;

关键词：

OPENING METATHESIS POLYMERIZATION; CYCLIZATION; COMPLEXES; CYCLOPROPANATION; DIAZOACETATE;

D O I：

10.1021/ol202812d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Grubbs first-generation catalyst has been found to be an effective catalyst for the synthesis of enaminones by coupling thioamides with alpha-diazodicarbonyl compounds. The reaction is successful in converting primary, secondary, and tertiary thioamides into their corresponding enaminones. The reaction is also suitable for the synthesis of chiral enaminones.

引用

页码：440 / 443

页数：4

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