Breast-feeding of allergic infants

被引:113
作者
Isolauri, E [1 ]
Tabvanainen, A
Peltola, T
Arvola, T
机构
[1] Univ Turku, Dept Pediat, FIN-20520 Turku, Finland
[2] Tampere Univ Hosp, Dept Pediat, Tampere, Finland
基金
芬兰科学院;
关键词
D O I
10.1016/S0022-3476(99)70368-9
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective: Infants may have allergic disease even during exclusive breastfeeding. The aim of-this study was to evaluate whether allergic infants should continue breast-feeding. Study design: We studied 100 infants who had atopic eczema during exclusive breast-teed;ng. The extent and severity of the eczema, allergic sensitization, and the patients' growth and nutrition were assessed during and after cessation of breast-feeding. Results: The mean body length SD score decreased at the onset of allergic disease, and an association was seen between the duration of symptoms and poor growth (r = -.23, P =.04). Some improvement could be achieved by strict elimination diet by the mothers. The atopic eczema improved significantly after breast-feeding was stopped: SCORAD score 20 (range 15 to 27) during and 7 (range 4 to 11) after breast-feeding t = 5.38, P <.0001, and the relative length of patients increased, in parallel with improved nutritional parameters. Conclusions: Breast-feeding should be promoted for primary prevention of allergy, but breast-fed infants with allergy should be treated by allergen avoidance, and in some cases breast-feeding should also be stopped. This particularly applies to infants with atopic eczema who also have impaired growth.
引用
收藏
页码:27 / 32
页数:6
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