Full genome sequences of two virulent strains of peste-des-petits ruminants virus, the Cote d'Ivoire 1989 and Nigeria 1976 strains

被引:41
作者
Chard, Louisa S. [1 ]
Bailey, Dalan S. [2 ]
Dash, Pradyot [3 ]
Banyard, Ashley C. [1 ]
Barrett, Thomas [1 ]
机构
[1] Inst Anim Hlth, Pirbright Lab, Woking GU24 0NF, Surrey, England
[2] Univ London Imperial Coll Sci Technol & Med, Dept Virol, Fac Med, London W2 1PG, England
[3] St Jude Childrens Res Hosp, Dept Immunol, Doherty Lab, Memphis, TN 38105 USA
基金
英国生物技术与生命科学研究理事会; 英国惠康基金;
关键词
Morbillivirus; pestes-des-petits ruminants; genome; promoters; proteins;
D O I
10.1016/j.virusres.2008.04.018
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Peste-des-petits ruminants virus (PPRV) causes acute febrile illness in both farmed and wild small ruminants, with associated mortality rates of 50-80%. PPRV is a member of the Morbillivirus genus within the Paramyxovirus family and although there are many full length genome sequences available for members of this family, their availability for PPRV in particular is limited. We have determined the full length sequences representing two virulent strains of PPRV, the Cote d'Ivoire 1989 (CI/89) and Nigeria 1976 (Ng76/1) strains. We present an alignment of the promoter regions of these viruses with other available PPRV promoter sequences and have identified domains in PPRV proteins believed to be critical for paramyxovirus promoter attenuation. We have also analysed the proteins of these viruses, comparing them to other available PPRV protein sequences and identified motifs that were previously recognised as being required for the function of other paramyxovirus proteins. (c) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:192 / 197
页数:6
相关论文
共 37 条
[1]   Full genome sequence of peste des petits ruminants virus, a member of the Morbillivirus genus [J].
Bailey, D ;
Banyard, A ;
Dash, P ;
Ozkul, A ;
Barrett, T .
VIRUS RESEARCH, 2005, 110 (1-2) :119-124
[2]   Reverse genetics for peste-des-petits-ruminants virus (PPRV): Promoter and protein specificities [J].
Bailey, Dalan ;
Chard, Louisa S. ;
Dash, Pradyot ;
Barrett, Tom ;
Banyard, Ashley C. .
VIRUS RESEARCH, 2007, 126 (1-2) :250-255
[3]   A role for virus promoters in determining the pathogenesis of Rinderpest virus in cattle [J].
Banyard, AC ;
Baron, MD ;
Barrett, T .
JOURNAL OF GENERAL VIROLOGY, 2005, 86 :1083-1092
[4]   THE SEQUENCE OF THE N-GENE AND L-GENE OF RINDERPEST VIRUS, AND THE 5' AND 3' EXTRA-GENIC SEQUENCES - THE COMPLETION OF THE GENOME SEQUENCE OF THE VIRUS [J].
BARON, MD ;
BARRETT, T .
VETERINARY MICROBIOLOGY, 1995, 44 (2-4) :175-185
[5]   CLONING AND SEQUENCE-ANALYSIS OF THE MATRIX (M) PROTEIN GENE OF RINDERPEST VIRUS AND EVIDENCE FOR ANOTHER BOVINE MORBILLIVIRUS [J].
BARON, MD ;
GOATLEY, L ;
BARRETT, T .
VIROLOGY, 1994, 200 (01) :121-129
[6]  
BARRETT T, 2005, RINDERPEST PESTES PE, P13
[7]   Conformational flexibility in recombinant measles virus nucleocapsids visualised by cryo-negative stain electron microscopy and real-space helical reconstruction [J].
Bhella, D ;
Ralph, A ;
Yeo, RP .
JOURNAL OF MOLECULAR BIOLOGY, 2004, 340 (02) :319-331
[8]   MOLECULAR-CLONING OF NATURAL PARAMYXOVIRUS COPY-BACK DEFECTIVE INTERFERING RNAS AND THEIR EXPRESSION FROM DNA [J].
CALAIN, P ;
CURRAN, J ;
KOLAKOFSKY, D ;
ROUX, L .
VIROLOGY, 1992, 191 (01) :62-71
[9]   THE RULE OF 6, A BASIC FEATURE FOR EFFICIENT REPLICATION OF SENDAI VIRUS DEFECTIVE INTERFERING RNA [J].
CALAIN, P ;
ROUX, L .
JOURNAL OF VIROLOGY, 1993, 67 (08) :4822-4830
[10]   Mutation of YMYL in the Nipah virus matrix protein abrogates budding and alters subcellular localization [J].
Ciancanelli, Michael J. ;
Basler, Christopher F. .
JOURNAL OF VIROLOGY, 2006, 80 (24) :12070-12078