HGF Guides T Cells into the Heart

被引:6
作者
Wolf, Dennis [1 ]
Li, Jie [1 ]
Ley, Klaus [1 ]
机构
[1] La Jolla Inst Allergy & Immunol, Div Inflammat Biol, La Jolla, CA 92037 USA
关键词
RECEPTOR EXPRESSION; LYMPHOCYTES; REJECTION;
D O I
10.1016/j.immuni.2015.06.001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Expression of distinct homing receptors guides adaptive immune cells to antigen-rich tissue. In this issue of Immunity, Komarowska et al. (2015) describe an autocrine loop that is initiated by cardiac-expressed hepatocyte growth factor to direct T cells into the heart during inflammation and cardiac transplant rejection.
引用
收藏
页码:979 / 981
页数:4
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