Is natalizumab overshooting its rebound?

被引:9
作者
Fox, Robert J. [1 ]
Kappos, Ludwig [2 ]
机构
[1] Cleveland Clin Fdn, Mellen Ctr Multiple Sclerosis, Cleveland, OH 44195 USA
[2] Univ Basel Hosp, Res Dept, Basel, Switzerland
关键词
D O I
10.1212/01.wnl.0000306415.37679.5a
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:1073 / 1074
页数:2
相关论文
共 10 条
[1]   The incidence and significance of anti-natalizumab antibodies -: Results from AFFIRM and SENTINEL [J].
Calabresi, P. A. ;
Giovannoni, G. ;
Confavreux, C. ;
Galetta, S. L. ;
Havrdova, E. ;
Hutchinson, M. ;
Kappos, L. ;
Miller, D. H. ;
O'Connor, P. W. ;
Phillips, J. T. ;
Polman, C. H. ;
Radue, E. -W. ;
Rudick, R. A. ;
Stuart, W. H. ;
Lublin, F. D. ;
Wajgt, A. ;
Weinstock-Guttman, B. ;
Wynn, D. R. ;
Lynn, F. ;
Panzara, M. A. ;
Macdonell, R. ;
Hughes, A. ;
Taylor, I. ;
Lee, Y. C. ;
Ma, H. ;
King, J. ;
Kilpatrick, T. ;
Butzkueven, H. ;
Marriott, M. ;
Pollard, J. ;
Spring, P. ;
Spies, J. ;
Barnett, M. ;
Dehaene, I. ;
Vanopdenbosch, L. ;
D'Hooghe, M. ;
Van Zandijcke, M. ;
Derijck, O. ;
Seeldrayers, P. ;
Jacquy, J. ;
Piette, T. ;
De Cock, C. ;
Medaer, R. ;
Soors, P. ;
Vanroose, E. ;
Vanderhoven, L. ;
Nagels, G. ;
Dubois, B. ;
Deville, M. -C. ;
D'Haene, R. .
NEUROLOGY, 2007, 69 (14) :1391-1403
[2]   A controlled trial of natalizumab for relapsing multiple sclerosis. [J].
Miller, DH ;
Khan, OA ;
Sheremata, WA ;
Blumhardt, LD ;
Rice, GPA ;
Libonati, MA ;
Willmer-Hulme, AJ ;
Dalton, CM ;
Miszkiel, KA ;
O'Connor, PW .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (01) :15-23
[3]  
O'Connor PW, 2006, MULT SCLER, V12, pS17
[4]   Randomized multicenter trial of natalizumab in acute MS relapses - Clinical and MRI effects [J].
O'Connor, PW ;
Goodman, A ;
Willmer-Hulme, AJ ;
Libonati, MA ;
Metz, L ;
Murray, RS ;
Sheremata, WA ;
Vollmer, TL ;
Stone, LA .
NEUROLOGY, 2004, 62 (11) :2038-2043
[5]   A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis [J].
Polman, CH ;
O'Connor, PW ;
Havrdova, E ;
Hutchinson, M ;
Kappos, L ;
Miller, DH ;
Phillips, JT ;
Lublin, FD ;
Giovannoni, G ;
Wajgt, A ;
Toal, M ;
Lynn, F ;
Panzara, MA ;
Sandrock, AW .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (09) :899-910
[6]   Linomide in the treatment of multiple sclerosis:: MRI results from prematurely terminated phase-III trials [J].
Tan, IL ;
Lycklama à Nijeholt, GJ ;
Polman, CH ;
Adèr, HJ ;
Barkhof, F .
MULTIPLE SCLEROSIS, 2000, 6 (02) :99-104
[7]   Differential effects of treatment with a small-molecule VLA-4 antagonist before and after onset of relapsing EAE [J].
Theien, BE ;
Vanderlugt, CL ;
Nickerson-Nutter, C ;
Cornebise, M ;
Scott, DM ;
Perper, SJ ;
Whalley, ET ;
Miller, SD .
BLOOD, 2003, 102 (13) :4464-4471
[8]   The effect of anti-α4 integrin antibody on brain lesion activity in MS [J].
Tubridy, N ;
Behan, PO ;
Capildeo, R ;
Chaudhuri, A ;
Forbes, R ;
Hawkins, CP ;
Hughes, RAC ;
Palace, J ;
Sharrack, B ;
Swingler, R ;
Young, C ;
Moseley, IF ;
MacManus, DG ;
Donoghue, S ;
Miller, DH .
NEUROLOGY, 1999, 53 (03) :466-472
[9]   Postwithdrawal rebound increase in T2 lesional activity in natalizumab-treated MS patients [J].
Vellinga, M. M. ;
Castelijns, J. A. ;
Barkhof, F. ;
Uitdehaag, B. M. J. ;
Polman, C. H. .
NEUROLOGY, 2008, 70 (13) :1150-1151
[10]   Linomide in relapsing and secondary progressive MS -: Part II:: MRI results [J].
Wolinsky, JS ;
Narayana, PA ;
Noseworthy, JH ;
Lublin, FD ;
Whitaker, JN ;
Linde, A ;
Gjörstrup, P ;
Sullivan, HC .
NEUROLOGY, 2000, 54 (09) :1734-1741