Advanced Technologies for the Extraction of Marine Brown Algal Polysaccharides

被引：207
作者：
Dobrincic, Ana [1 ]
Balbino, Sandra [1 ]
Zoric, Zoran [1 ]
Pedisic, Sandra [1 ]
Kovacevic, Danijela Bursac [1 ]
Garofulic, Ivona Elez [1 ]
Dragovic-Uzelac, Verica [1 ]
机构：
[1] Univ Zagreb, Fac Food Technol & Biotechnol, Pierottijeva 6, Zagreb 10000, Croatia
来源：
MARINE DRUGS | 2020年 / 18卷 / 03期
关键词：
polysaccharides; marine algae; extraction; fucoidan; laminarin; alginate; MICROWAVE-ASSISTED EXTRACTION; ALGINATE-CHITOSAN MICROSPHERES; WATER-SOLUBLE POLYSACCHARIDES; DRUG-DELIVERY-SYSTEM; SULFATED POLYSACCHARIDES; CONTROLLED-RELEASE; CALCIUM ALGINATE; SODIUM ALGINATE; STRUCTURAL-CHARACTERIZATION; ANTIINFLAMMATORY ACTIVITY;
D O I：
10.3390/md18030168
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Over the years, brown algae bioactive polysaccharides laminarin, alginate and fucoidan have been isolated and used in functional foods, cosmeceutical and pharmaceutical industries. The extraction process of these polysaccharides includes several complex and time-consuming steps and the correct adjustment of extraction parameters (e.g., time, temperature, power, pressure, solvent and sample to solvent ratio) greatly influences the yield, physical, chemical and biochemical properties as well as their biological activities. This review includes the most recent conventional procedures for brown algae polysaccharides extraction along with advanced extraction techniques (microwave-assisted extraction, ultrasound assisted extraction, pressurized liquid extraction and enzymes assisted extraction) which can effectively improve extraction process. The influence of these extraction techniques and their individual parameters on yield, chemical structure and biological activities from the most current literature is discussed, along with their potential for commercial applications as bioactive compounds and drug delivery systems.
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页数：29
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