Self-assembly of Amphiphilic Peptide in Phospholipid Membrane

被引:0
|
作者
Kawakita, Anju [1 ]
Uchida, Noriyuki [1 ]
Ryu, Yunosuke [1 ]
Muraoka, Takahiro [1 ]
机构
[1] Tokyo Univ Agr & Technol, Grad Sch Engn, Dept Appl Chem, 2-24-16 Nakacho, Koganei, Tokyo 1848588, Japan
关键词
Peptide; Phospholipid; Self-assembly; Fluorescence microscopy; Vesicle; LIPID RAFTS;
D O I
10.2494/photopolymer.34.155
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
An amphiphilic molecule Lipid-(RADA) 2 consisting of a repeating RADA peptide sequence and alkyl chains appending a fluorescent nitrobenzoxadiazole (NBD) dye, was synthesized. In a fluorescence microscopic observation, localization of an aggregate containing Lipid-(RADA) 2 at a bilayer membrane formed with 1,2-dioleoyl-sn-glycero-3-phosphocholine ( DOPC) was observed.
引用
收藏
页码:155 / 159
页数:5
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