The conversion of aryl and heteroaryl methylketones to the corresponding secondary or tertiary amides

被引：8

作者：

Ding, Jiaoyang ^{[1
]}

Cao, Liping ^{[1
]}

Wang, Jungang ^{[1
]}

Xue, Weijian ^{[1
]}

Zhu, Yanping ^{[1
]}

Wu, Anxin ^{[1
]}

机构：

[1] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2011年 / 05期

基金：

中国国家自然科学基金;

关键词：

iodine; amide; water; Lieben iodoform reaction; BECKMANN REARRANGEMENT; BOND-CLEAVAGE; AMINES; EFFICIENT; ALCOHOLS; KETONES; AMIDATION; ALDEHYDES; ROUTE; ACIDS;

D O I：

10.3184/174751911X13053065216840

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Secondary or tertiary amides have been prepared directly from aryl, heteroaryl methyl ketones using an iodine-amine-NaOH system which afforded the expected products in good yields in an aqueous medium. The present method has the advantages of using inexpensive reagents, mild reaction condition and ease of manipulation.

引用

页码：298 / 301

页数：4

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