Characterization of murine leukemia virus restriction in mammals

被引：53

作者：

Besnier, C

Ylinen, L

Strange, B

Lister, A

Takeuchi, Y

Goff, SP

Towers, GJ

机构：

[1] UCL, Wohl Virion Ctr, Dept Immunol & Mol Pathol, London W1T 4JF, England

[2] UCL, Dept Biol, London WC1E 6BT, England

[3] Columbia Univ Coll Phys & Surg, Dept Biochem & Mol Biophys, New York, NY 10032 USA

[4] Columbia Univ Coll Phys & Surg, Howard Hughes Med Inst, New York, NY 10032 USA

来源：

JOURNAL OF VIROLOGY | 2003年 / 77卷 / 24期

关键词：

D O I：

10.1128/JVI.77.24.13403-13406.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Restriction of murine leukemia virus (MLV) was examined in cells from a range of mammals. All nonmurine restrictions were saturable blocks to N-tropic MLV infection, and several were prior to reverse transcription. We demonstrate restriction in cells from bat and show that if we express the murine restriction factor Fv1 in human cells, then Fv1, not the human host, defines the stage at which infection is blocked.

引用

页码：13403 / 13406

页数：4

共 24 条

[11] EFFECT OF FV-1 GENE-PRODUCT ON SYNTHESIS OF LINEAR AND SUPERCOILED VIRAL-DNA IN CELLS INFECTED WITH MURINE LEUKEMIA-VIRUS
JOLICOEUR, P
RASSART, E
[J]. JOURNAL OF VIROLOGY, 1980, 33 (01) : 183 - 195
[12] Jolicoeur P, 1979, Curr Top Microbiol Immunol, V86, P67
[13] Single amino acid changes in the murine leukemia virus capsid protein gene define the target of Fv1 resistance
Kozak, CA
Chakraborti, A
[J]. VIROLOGY, 1996, 225 (02) : 300 - 305
[14] A dominant block to HIV-1 replication at reverse transcription in simian cells
Münk, C
Brandt, SM
Lucero, G
Landau, NR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (21) : 13843 - 13848
[15] Molecular phylogenetics and the origins of placental mammals
Murphy, WJ
Eizirik, E
Johnson, WE
Zhang, YP
Ryder, OA
O'Brien, SJ
[J]. NATURE, 2001, 409 (6820) : 614 - 618
[16] INHERITANCE OF SUSCEPTIBILITY TO FRIEND MOUSE LEUKEMIA VIRUS .V. INTRODUCTION OF A GENE RESPONSIBLE FOR SUSCEPTIBILITY IN GENETIC COMPLEMENT OF RESISTANT MICE
ODAKA, T
[J]. JOURNAL OF VIROLOGY, 1969, 3 (06) : 543 - &
[17] MAJOR GENETIC LOCUS AFFECTING RESISTANCE TO INFECTION WITH MURINE LEUKEMIA VIRUSES .2. APPARENT IDENTITY TO A MAJOR LOCUS DESCRIBED FOR RESISTANCE TO FRIEND MURINE LEUKEMIA VIRUS
PINCUS, T
ROWE, WP
LILLY, F
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1971, 133 (06) : 1234 - &
[18] Molecular evidence from retroposons that whales form a clade within even-toed ungulates
Shimamura, M
Yasue, H
Ohshima, K
Abe, H
Kato, H
Kishiro, T
Goto, M
Munechika, I
Okada, N
[J]. NATURE, 1997, 388 (6643) : 666 - 670
[19] Abrogation of Ref1 retrovirus restriction in human cells
Towers, G
Collins, M
Takeuchi, Y
[J]. JOURNAL OF VIROLOGY, 2002, 76 (05) : 2548 - 2550
[20] A conserved mechanism of retrovirus restriction in mammals
Towers, G
Bock, M
Martin, S
Takeuchi, Y
Stoye, JP
Danos, O
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (22) : 12295 - 12299

← 1 2 3 →