Infrastructure and clinical practice for the detection and management of trauma-associated haemorrhage and coagulopathy

被引:7
作者
Driessen, A. [1 ,2 ]
Schaefer, N. [2 ]
Albrecht, V. [2 ]
Schenk, M. [2 ]
Froehlich, M. [1 ]
Stuermer, E. K. [2 ]
Maegele, M. [1 ,2 ]
机构
[1] Univ Witten Herdecke, CMMC, Dept Orthopaed Surg Traumatol & Sports Traumatol, D-51109 Cologne, Germany
[2] Univ Witten Herdecke, Inst Res Operat Med IFOM, D-51109 Cologne, Germany
关键词
Trauma-haemorrhage; Coagulopathy; Coagulation assays; Management; Blood products; Haemostatic agents; Anticoagulants; FRESH-FROZEN PLASMA; MASSIVE TRANSFUSION; WHOLE-BLOOD; MORTALITY; PROTOCOL; THERAPY; BENEFIT; DEATHS; RATIOS; RISK;
D O I
10.1007/s00068-014-0455-y
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Early detection and management of post-traumatic haemorrhage and coagulopathy have been associated with improved outcomes, but local infrastructures, logistics and clinical strategies may differ. To assess local differences in infrastructure, logistics and clinical management of trauma-associated haemorrhage and coagulopathy, we have conducted a web-based survey amongst the delegates to the 15th European Congress of Trauma and Emergency Surgery (ECTES) and the 2nd World Trauma (WT) Congress held in Frankfurt, Germany, 25-27 May 2014. 446/1,540 delegates completed the questionnaire yielding a response rate of 29 %. The majority specified to work as consultants/senior physicians (47.3 %) in general (36.1 %) or trauma/orthopaedic surgery (44.5 %) of level I (70 %) or level II (19 %) trauma centres. Clinical assessment (> 80 %) and standard coagulation assays (74.6 %) are the most frequently used strategies for early detection and monitoring of bleeding trauma patients with coagulopathy. Only 30 % of the respondents declared to use extended coagulation assays to better characterise the bleeding and coagulopathy prompted by more individualised treatment concepts. Most trauma centres (69 %) have implemented local protocols based on international and national guidelines using conventional blood products, e.g. packed red blood cell concentrates (93.3 %), fresh frozen plasma concentrates (93.3 %) and platelet concentrates (83 %), and antifibrinolytics (100 %). 89 % considered the continuous intake of anticoagulants including "new oral anticoagulants" and platelet inhibitors as an increasing threat to bleeding trauma patients. This study confirms differences in infrastructure, logistics and clinical practice for the detection and management of trauma-haemorrhage and trauma-associated coagulopathy amongst international centres. Ongoing work will focus on geographical differences.
引用
收藏
页码:413 / 420
页数:8
相关论文
共 38 条
[1]  
*AM COLL SURG COMM, 2008, ADV TRAUM LIF SUPP D
[2]  
[Anonymous], J TRAUMA
[3]  
[Anonymous], J R ARMY MED CORPS
[4]  
BELLAMY RF, 1984, MIL MED, V149, P55
[5]   'New' direct oral anticoagulants in the perioperative setting [J].
Breuer, Georg ;
Weiss, Dominik R. ;
Ringwald, Juergen .
CURRENT OPINION IN ANESTHESIOLOGY, 2014, 27 (04) :409-419
[6]   Acute traumatic coagulopathy [J].
Brohi, K ;
Singh, J ;
Heron, M ;
Coats, T .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2003, 54 (06) :1127-1130
[7]   Tranexamic Acid for Trauma Patients: A Critical Review of the Literature [J].
Cap, Andrew P. ;
Baer, David G. ;
Orman, Jean A. ;
Aden, James ;
Ryan, Kathy ;
Blackbourne, Lorne H. .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2011, 71 :S9-S14
[8]   Predefined Massive Transfusion Protocols are Associated With a Reduction in Organ Failure and Postinjury Complications [J].
Cotton, Bryan A. ;
Au, Brigham K. ;
Nunez, Timothy C. ;
Gunter, Oliver L. ;
Robertson, Amy M. ;
Young, Pampee P. .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2009, 66 (01) :41-48
[9]   Hemostatic Effects of Fresh Frozen Plasma May be Maximal at Red Cell Ratios of 1:2 [J].
Davenport, Ross ;
Curry, Nicola ;
Manson, Joanna ;
De'Ath, Henry ;
Coates, Amy ;
Rourke, Claire ;
Pearse, Rupert ;
Stanworth, Simon ;
Brohi, Karim .
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2011, 70 (01) :90-96
[10]  
Dente C, 2011, J TRAUMA, V70, P388