Influence of electron beam irradiation on physicochemical properties of poly(trimethylene carbonate)

被引：15

作者：

Jozwiakowska, Joanna ^{[1
]}

Wach, Radoslaw A. ^{[1
]}

Rokita, Bozena ^{[1
]}

Ulanski, Piotr ^{[1
]}

Nalawade, Sameer P. ^{[2
]}

Grijpma, Dirk W. ^{[2
,3
]}

Feijen, Jan ^{[2
]}

Rosiak, Janusz M. ^{[1
]}

机构：

[1] Tech Univ Lodz, Inst Appl Radiat Chem, PL-93590 Lodz, Poland

[2] Univ Twente, Fac Sci & Technol, Dept Polymer Chem & Biomat, Inst Biomed Technol BMTI, NL-7500 AE Enschede, Netherlands

[3] Univ Groningen, Univ Med Ctr Groningen, Dept Biomed Engn, NL-9700 AD Groningen, Netherlands

来源：

POLYMER DEGRADATION AND STABILITY | 2011年 / 96卷 / 08期

关键词：

Degradation; Crosslinking; Electron beam irradiation; Molecular weight changes; Poly(trimethylene carbonate); MOLECULAR-SIZE DISTRIBUTION; CROSS-LINKING; TRIMETHYLENE CARBONATE; EPSILON-CAPROLACTONE; POLYMERS; RADIATION; DEGRADATION; BEHAVIOR; SCISSION; ACID);

D O I：

10.1016/j.polymdegradstab.2011.05.010

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Electron beam (EB) irradiation of poly(trimethylene carbonate) (PTMC), an amorphous, biodegradable polymer used in the field of biomaterials, results in predominant cross-linking and finally in the formation of gel fraction, thus enabling modification of physicochemical properties of this material without significant changes in its chemical structure. PTMC films (M-w: 167-553 kg mol(-1)) were irradiated with different doses using an electron accelerator. Irradiation with a standard sterilization dose of 25 kGy caused neither significant changes in the chemical composition of the polymer nor significant deterioration of its mechanical properties. Changes in viscosity-, number-, weight-, and z-average molecular weights of PTMC for doses lower than the gelation dose (D-g) as well as gel sol analysis and swelling tests for doses above D-g indicate domination of cross-linking over degradation. EB irradiation can be considered as an effective tool for increasing the average molecular weight of PTMC and sterilization of PTMC-based biomaterials. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：1430 / 1437

页数：8

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