Integrative/Hybrid Methods Structural Biology: Role of Macromolecular Crystallography

被引：2
作者：
Burley, Stephen K. [1 ]
机构：
[1] Rutgers State Univ, Piscataway, NJ 08854 USA
来源：
INTEGRATIVE STRUCTURAL BIOLOGY WITH HYBRID METHODS | 2018年 / 1105卷
关键词：
X-ray crystallography; Macromolecular crystallography; MX; Protein crystallography; 3D structure; Protein; DNA; RNA; Protein data Bank; PDB; Worldwide protein data Bank; wwPDB; Atomic coordinates; Structural biology; Integrative/hybrid methods; I/H methods; PROTEIN; PDB; VALIDATION; REFINEMENT; SYSTEM; MODEL;
D O I：
10.1007/978-981-13-2200-6_2
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Macromolecular crystallography has been central to the emergence and development of structural biology as a scientific discipline. Approximately 90% of the more than 138,000 three-dimensional structures currently available in the Protein Data Bank (PDB) archive, the single, global open access data resource for macromolecular structure data, were determined using X-ray crystallography. MX, the enormous variety of PDB structures of proteins, DNA, and RNA, and computational models derived therefrom will be central to the growth of integrative or hybrid (I/H) methods structural studies of macromolecular assemblies and other complex biological systems.
引用
收藏
页码：11 / 18
页数：8
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