Quantitative Analysis of Marker Compounds in Angelica gigas, Angelica sinensis, and Angelica acutiloba by HPLC/DAD

被引：46

作者：

Jeong, Su Yang ^{[1
]}

Kim, Hye Mi ^{[1
]}

Lee, Kyu Ha ^{[1
]}

Kim, Kyu Yeob ^{[1
]}

Huang, Dae Sun ^{[1
]}

Kim, Jong Hwan ^{[1
]}

Seong, Rack Seon ^{[1
]}

机构：

[1] Minist Food & Drug Safety, Herbal Med Res Div, Natl Inst Food & Drug Safety Evaluat, Chungcheongbuk Do 363700, South Korea

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2015年 / 63卷 / 07期

关键词：

Angelica gigas; Angelica acutiloba; Angelica sinensis; HPLC/diode-array detector (DAD); PERFORMANCE LIQUID-CHROMATOGRAPHY; UMBELLIFERAE PLANTS; DECURSINOL ANGELATE; ROOTS; CONSTITUENTS;

D O I：

10.1248/cpb.c15-00081

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Although Danggui is the root of Angelica gigas NAKAI in the Korean Pharmacopoeia, it is determined that Danggui is also the root of Angelica sinensis (OLIV.) DIELS in China and Hong Kong, as well as the root of Angelica acutiloba KITAGAWA in Japan. Accordingly, we tried to develop an identification method using the main compounds in A. gigas, A. sinensis, and A. acutiloba through HPLC/diode-array detector (DAD). This method was fully validated for linearity, accuracy, precision, recovery, and robustness. Multivariate analysis was also implemented after pattern analysis and monitoring. As a result, each compound pattern of A. gigas, A. sinensis, and A. acutiloba was identified, making it possible to distinguish them from each other.

引用

页码：504 / 511

页数：8

共 22 条

[1] The simultaneous determination of coumarins in Angelica gigas root by high performance liquid chromatography-diode array detector coupled with electrospray ionization/mass spectrometry
Ahn, Mi-Jeong
Lee, Mi Kyeong
Kim, Young Choong
Sung, Sang Hyun
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2008, 46 (02) : 258 - 266
[2] BOHRMANN H, 1967, CHEM PHARM BULL, V15, P1606
[3] Chi H. J., 1970, Korean Journal of Pharmacognosy, V1, P25
[4] Chi H. J., 1988, KOR J PHARMACOGN, V19, P239
[5] Chinese Pharmacopoeia Committee, 2010, CHIN MED SCI TECHN P, P124
[6] Choi YE, 2000, BIOL PHARM BULL, V23, P884, DOI 10.1248/bpb.23.884
[7] Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis
Deng, SX
Chen, SN
Yao, P
Nikolic, D
Van Breemen, RB
Bolton, JL
Fong, HHS
Farnsworth, NR
Pauli, GF
[J]. JOURNAL OF NATURAL PRODUCTS, 2006, 69 (04): : 536 - 541
[8] Department of Health, 2005, HONG KONG CHIN MAT M, V1, P41
[9] Food Korea, 2012, KOR PHARM 10 MON 2, P1260
[10] 김선애, 2011, [Journal of Korean Medicine, 대한한의학회지], V32, P1

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