Quantitative Analysis of Marker Compounds in Angelica gigas, Angelica sinensis, and Angelica acutiloba by HPLC/DAD

被引：48

作者：

Jeong, Su Yang ^{[1
]}

Kim, Hye Mi ^{[1
]}

Lee, Kyu Ha ^{[1
]}

Kim, Kyu Yeob ^{[1
]}

Huang, Dae Sun ^{[1
]}

Kim, Jong Hwan ^{[1
]}

Seong, Rack Seon ^{[1
]}

机构：

[1] Minist Food & Drug Safety, Herbal Med Res Div, Natl Inst Food & Drug Safety Evaluat, Chungcheongbuk Do 363700, South Korea

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2015年 / 63卷 / 07期

关键词：

Angelica gigas; Angelica acutiloba; Angelica sinensis; HPLC/diode-array detector (DAD); PERFORMANCE LIQUID-CHROMATOGRAPHY; UMBELLIFERAE PLANTS; DECURSINOL ANGELATE; ROOTS; CONSTITUENTS;

D O I：

10.1248/cpb.c15-00081

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Although Danggui is the root of Angelica gigas NAKAI in the Korean Pharmacopoeia, it is determined that Danggui is also the root of Angelica sinensis (OLIV.) DIELS in China and Hong Kong, as well as the root of Angelica acutiloba KITAGAWA in Japan. Accordingly, we tried to develop an identification method using the main compounds in A. gigas, A. sinensis, and A. acutiloba through HPLC/diode-array detector (DAD). This method was fully validated for linearity, accuracy, precision, recovery, and robustness. Multivariate analysis was also implemented after pattern analysis and monitoring. As a result, each compound pattern of A. gigas, A. sinensis, and A. acutiloba was identified, making it possible to distinguish them from each other.

引用

页码：504 / 511

页数：8

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