A simple detection platform based on molecularly imprinted polymer for AFB1 and FuB1 mycotoxins

被引：35

作者：

Singh, Avinash Kumar ^{[1
,2
]}

Lakshmi, G. B. V. S. ^{[1
]}

Fernandes, Manuel ^{[3
]}

Sarkar, Tanushri ^{[3
]}

Gulati, Payal ^{[1
]}

Singh, Ravindra Pratap ^{[3
]}

Solanki, Pratima R. ^{[1
]}

机构：

[1] Jawaharlal Nehru Univ, Special Ctr Nanosci, Nanobio Lab D, New Delhi 110067, India

[2] Jawaharlal Nehru Univ, Sch Phys Sci, New Delhi 110067, India

[3] Indira Gandhi Natl Tribal Univ, Fac Sci, Dept Biotechnol, Amarkantak 484887, Madhya Pradesh, India

来源：

MICROCHEMICAL JOURNAL | 2021年 / 171卷

关键词：

Aflatoxin B1; Fumonisin B1; Molecularly imprinted polymer; Electrochemical biosensor; Polyaniline; AFLATOXIN; IMPACT;

D O I：

10.1016/j.microc.2021.106730

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The sensitive electrochemical sensing platforms were fabricated using molecularly imprinted polymer (MIP) based technique for mycotoxins [Aflatoxin B1 (AFB1) and Fumonisin B1 (FuB1)] detection. Polyaniline was used as a MIP matrix synthesized using the chemical oxidative polymerization method in the presence of AFB1 and FuB1toxins as the template molecules. Fourier transform infrared spectroscopy and electrochemical techniques were used for the characterization of the synthesized MIPs. The proposed biosensors exhibited good sensitivity of 7.037 and 9.092 mu A mL ng-1 cm-2 with the lower detection limits of 0.313 and 0.322 pg mL-1 for AFB1 and FuB1. Both sensors showed good linearity amidst the sensing range of 1 pg mL-1 to 500 ng mL-1. The fabricated sensors open up a promising strategy to detect AFB1 and FuB1 as an alternative for biomolecules with enormous specificity, quick responsiveness, and cost-effectiveness. These fabricated sensors manifest good analytical performance compared to other reported MIP-based sensors for AFB1 and FuB1 detection.

引用

页数：7