Do findings from new trials for schizophrenia fit with existing evidence: not duped ... just beguiled?

被引：7

作者：

Adams, Clive E. ^{[1
]}

Jayaram, Mahesh ^{[1
]}

机构：

[1] Univ Nottingham, Div Psychiat, Cochrane Schizophrenia Grp, Nottingham NG3 6AA, England

来源：

EPIDEMIOLOGIA E PSICHIATRIA SOCIALE-AN INTERNATIONAL JOURNAL FOR EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES | 2007年 / 16卷 / 03期

关键词：

D O I：

10.1017/S1121189X00002281

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

No treatment has caused a greater revolution in the treatment of people with schizophrenia than chlorpromazine. The new generation of drugs has been embraced by psychiatry with an enthusiasm fostered by the unmet needs of both patients and industry. Recent, independently funded trials have highlighted already existing data illustrating how the new antipsychotics drugs are an additional advance but not a revolution. In this story there are lessons for psychiatry - to opt for science rather than seduction.

引用

页码：199 / 202

页数：4

共 32 条

[1]

Adams Clive E, 2002, Epidemiol Psichiatr Soc, V11, P144

[2] The schizophrenia drug-treatment paradox: pharmacological treatment based on best possible evidence may be hardest to practise in high-income countries [J].

Adams, Clive E. ;

Tharyan, Prathap ;

Coutinho, Evandro S. F. ;

Stroup, T. Scott .

BRITISH JOURNAL OF PSYCHIATRY, 2006, 189 :391-392

[3]

[Anonymous], COCHRANE DATABASE SY

[4] Improving the quality of reporting of randomized controlled trials - The CONSORT statement [J].

Begg, C ;

Cho, M ;

Eastwood, S ;

Horton, R ;

Moher, D ;

Olkin, I ;

Pitkin, R ;

Rennie, D ;

Schulz, KF ;

Simel, D ;

Stroup, DF .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 276 (08) :637-639

[5]

*CTR REV DISS, 2007, DRUG TREATM SCHIZ EF

[6] Olanzapine for schizophrenia [J].

Duggan, L ;

Fenton, M ;

Rathbone, J ;

Dardennes, R ;

El-Dosoky, A ;

Indran, S .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2005, (02)

[7]

DUGGAN L, 2000, COCHRANE DATABASE SY

[8] Lilly investigated in US over the marketing of olanzapine [J].

Dyer, Owen .

BRITISH MEDICAL JOURNAL, 2007, 334 (7586) :171-171

[9]

ELSAYEH HG, 2006, COCHRANE DATABASE SY

[10]

FREEMAN H, 1958, SCHIZOPHRENIA REV SY

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