Research of catecholamine metabolism peculiarities of the children with attention deficit hyperactivity disorder.

被引：0

作者：

Kasatikova, HV

Larionov, NP

Popkova, HV

Briazgunov, IP

机构：

[1] Vladimir State Pedag Univ, Chair Chem, Vladimir, Russia

[2] Russian Acad Med Sci, Gen Pathol & Pathophysiol Res Inst, Mechanisms Adaptat Lab, Moscow 125, Russia

[3] Russian Acad Med Sci, Childrens Hlth Res Ctr, Dept Funct Pathol, Moscow 117296, Russia

来源：

VOPROSY MEDITSINSKOI KHIMII | 2000年 / 46卷 / 05期

关键词：

catecholamines; Attention Deficit hyperactivity Disorder (ADHD); high-pressure liquid chromatography (HPLC);

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The aim of research was to study catecholamine excretion peculiarities of the children with attention deficit hyperactivity disorder (ADHD). 25 children at the age of 7-9 years took part in this research. High-pressure liquid chromatography (HPLC) was used for measuring the content of catecholamine. The content of catecholamine was defined in the morning samples of urine. The examination showed, that ADHD children had the basal level of epinephrine and norepinephrine more than the normal control in 3,9 and 5,3 times. After cognitive tests the content of norepinephrine reduced in the ADHD group in 2,1 times in the comparison with normal control. On the contrary content of epinephrine increased in 2,8 times. Conclusion. Simpatico-adrenal system hyperactivity (especially it's adrenals component) characterized ADHD children.

引用

页码：455 / 461

页数：7

共 17 条

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